Lead poisoning could reduce gene expression in humans

Scientists have unveiled a correlation between high blood lead levels in children and methylation of genes involved in haem synthesis and carcinogenesis, indicating a previously unknown mechanism for lead poisoning.

Researchers identify key steps in development of kidneys

The discovery of how certain key structures in the kidneys are formed could have important implications for treating renal fibrosis (or scarring), a feature of chronic kidney disease (CKD), according to a new study by a researcher ...

Scientists develop probes to detect acute kidney failure early

Scientists from Nanyang Technological University, Singapore (NTU Singapore) have developed a type of imaging probe that allows for earlier detection of acute kidney failure, a rapidly-developing condition that can be fatal.

Sensors detect disease markers in breath

A small, thin square of an organic plastic that can detect disease markers in breath or toxins in a building's air could soon be the basis of portable, disposable sensor devices. By riddling the thin plastic films with pores, ...

New polymer warns of dangerous kidney disease

The advanced phase of acute kidney injury can be fatal in up to half of patients. Researchers say it is now possible to detect the disease in its initial stages, when treatment is still relatively simple and the prognosis ...

Manatee in Caribbean repopulation scheme dies

One of two manatees released into the Caribbean in August under a pioneering repopulation scheme has died of a suspected kidney infection, the Guadeloupe National Park announced Monday.

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Renal failure

Renal failure or kidney failure is a situation in which the kidneys fail to function adequately. It is divided into acute and chronic forms; either form may be due to a large number of other medical problems.

Biochemically, it is typically detected by an elevated serum creatinine. In the science of physiology, renal failure is described as a decrease in the glomerular filtration rate. When the kidneys malfunction, problems frequently encountered are abnormal fluid levels in the body, deranged acid levels, abnormal levels of potassium, calcium, phosphate, hematuria (blood in the urine) and (in the longer term) anemia. Long-term kidney problems have significant repercussions on other diseases, such as cardiovascular disease.

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