Lead poisoning could reduce gene expression in humans

Scientists have unveiled a correlation between high blood lead levels in children and methylation of genes involved in haem synthesis and carcinogenesis, indicating a previously unknown mechanism for lead poisoning.

Researchers identify key steps in development of kidneys

The discovery of how certain key structures in the kidneys are formed could have important implications for treating renal fibrosis (or scarring), a feature of chronic kidney disease (CKD), according to a new study by a researcher ...

Sensors detect disease markers in breath

A small, thin square of an organic plastic that can detect disease markers in breath or toxins in a building's air could soon be the basis of portable, disposable sensor devices. By riddling the thin plastic films with pores, ...

How E. coli cells work in the human gut

(Phys.org) -- The bacterium Escherichia coli, commonly known as E. coli, has a duplicitous reputation. Scientists tell us that most strains of the microbe live peacefully in our guts or the guts of other mammals, munching ...

Adult kidney stem cells found in fish

(PhysOrg.com) -- It has long been a given that adult humans -- and mammals in general -- lack the capacity to grow new nephrons, the kidney?s delicate blood filtering tubules, which has meant that dialysis, and ultimately ...

How long is a piece of thread? Long enough to save a life

A discovery by Monash University scientists could see humble cotton thread emerge as a core material in low-cost 'lab-on-chip' devices capable of detecting diseases such as kidney failure and diabetes.

Lilies Deadly to Cats, Veterinarians Warn

Lilies, a floral reminder that winter has passed, frequently appear in homes during spring holidays as potted plants or cut flowers. But for cats, many lilies can be as lethal as they are lovely.

Scientists develop probes to detect acute kidney failure early

Scientists from Nanyang Technological University, Singapore (NTU Singapore) have developed a type of imaging probe that allows for earlier detection of acute kidney failure, a rapidly-developing condition that can be fatal.

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Renal failure

Renal failure or kidney failure is a situation in which the kidneys fail to function adequately. It is divided into acute and chronic forms; either form may be due to a large number of other medical problems.

Biochemically, it is typically detected by an elevated serum creatinine. In the science of physiology, renal failure is described as a decrease in the glomerular filtration rate. When the kidneys malfunction, problems frequently encountered are abnormal fluid levels in the body, deranged acid levels, abnormal levels of potassium, calcium, phosphate, hematuria (blood in the urine) and (in the longer term) anemia. Long-term kidney problems have significant repercussions on other diseases, such as cardiovascular disease.

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