Research teams from the National Institutes of Health and abroad have identified the first inhibitor of an enzyme long thought to be a potential drug target for fighting disease-causing parasites and bacteria. The teams, ...
Biochemistry
Apr 3, 2017
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A team of Michigan State University scientists has genetically sequenced two species of poisonous mushrooms, discovering that they can theoretically produce billions of compounds through one molecular assembly line. This ...
Biotechnology
Jan 24, 2017
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Take two poisonous mushrooms, and call me in the morning. While no doctor would ever write this prescription, toxic fungi may hold the secrets to tackling deadly diseases.
Biochemistry
Dec 4, 2014
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Swiss scientists have developed a new amino acid that can be used to modify the 3-D structure of therapeutic peptides. Insertion of the amino acid into bioactive peptides enhanced their binding affinity up to 40-fold. Peptides ...
Biochemistry
Aug 31, 2014
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Researchers have created tiny protein tubes named after the Roman god Janus which may offer a new way to accurately channel drugs into the body's cells.
Nanomaterials
Nov 14, 2013
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(PhysOrg.com) -- Researchers outline today a new approach in the potential development of drugs to counter a cellular defect that triggers Parkinson’s and other diseases.
Biochemistry
Jul 14, 2009
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Scientists at Tokyo Institute of Technology have developed a computational method based on large-scale molecular dynamics simulations to predict the cell-membrane permeability of cyclic peptides using a supercomputer. Their ...
Cell & Microbiology
Jul 13, 2021
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6
Because biopharmaceuticals are medium- and high-molecular-weight, biologically active macromolecules, they are not easily absorbed by the small intestine, resulting in a bottleneck for oral administration. Now, researchers ...
Biochemistry
Sep 21, 2017
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5
Many plants produce compounds that serve as a defense against predators or pathogens. Some are also used by humans for a variety of beneficial purposes, such as in medicines. As recently as the early 1990s, a unique class ...
Cell & Microbiology
Dec 12, 2011
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0
Whitehead Institute scientists have developed a rapid, inexpensive drug-screening method that could be used to target diseases that until now have stymied drug developers, such as Parkinson's disease. This technique uses ...
Biochemistry
Jul 13, 2009
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