C. difficile hypervirulence genes identified

Five genetic regions have been identified that are unique to the most virulent strain of Clostridium difficile (C. difficile), the hospital superbug. Researchers writing in BioMed Central's open access journal Genome Biology ...

A new tool for forecasting the behavior of the microbiome

A team of investigators from Brigham and Women's Hospital and the University of Massachusetts have developed a suite of computer algorithms that can accurately predict the behavior of the microbiome - the vast collection ...

C. difficile needs iron, but too much is hazardous

Those bacteria that require iron walk a tightrope. Iron is essential for their growth, but too much iron can damage DNA and enzymes through oxidation. Therefore, bacteria have machinery to maintain their intracellular iron ...

Molecular docking site of a bacterial toxin identified

Clostridium difficile is a dangerous intestinal bacterium that can cause severe diarrhoea and life-threatening intestinal infections after long-term treatment with antibiotics. The pharmacologists and toxicologists Prof. ...

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