How cells respond in the face of stress is a critical component of maintaining homeostasis and preventing disease, but its mechanisms are poorly understood. New research out of the University of Chicago has fit together another ...
Cell & Microbiology
Jan 18, 2021
0
26
A molecular biologist at the University of Massachusetts Amherst who has for decades studied the nightmarish group of fatal diseases caused by prions—chronic wasting disease in deer, mad cow in cattle and its human analog—credits ...
Molecular & Computational biology
May 6, 2020
0
162
Of the many marvels of the human immune system, the processing of antigens by the class I proteins of the major histocompatability complex (MHC-I) is among the most mind-boggling. Exactly how these proteins carry out their ...
Cell & Microbiology
Dec 3, 2019
0
116
Buried deep within the dazzlingly intricate machinery of the human cell could lie a key to treating a range of deadly cancers, according to a team of scientists at Florida State University.
Cell & Microbiology
Feb 26, 2019
0
96
X-ray and electron microscopy techniques help unfold the story of protein chaperones.
Biochemistry
Feb 25, 2019
0
16
Proteins are the workhorses of our cells, carrying out essential tasks to keep our cells – and our bodies – functioning properly. But proteins can only do their jobs if they fold into the right shape.
Cell & Microbiology
Nov 28, 2018
1
13
For decades, molecular biologists studying a class of molecular chaperones known as heat shock proteins (Hsp70s) have relied on the Hsp70s found in bacteria as the model system. Now one of the world's experts on the molecule ...
Biochemistry
Nov 9, 2018
0
54
Chaperones are specialized proteins in the cell that help other proteins to reach their functional 3-D shapes, which correspond to the states preferred at thermodynamic equilibrium. But a new study by EPFL, UNIL and INSERM ...
Biochemistry
Mar 5, 2018
0
12
Mitochondria are cell organelles that play critical roles in maintaining the cell's health, or homeostasis. One way that mitochondria do this is by harvesting energy though oxidative phosphorylation, where various enzymes ...
Cell & Microbiology
Nov 2, 2017
0
10
Influenza viruses mutate rapidly, which is why flu vaccines have to be redesigned every year. A new study from MIT sheds light on just how these viruses evolve so quickly, and offers a potential way to slow them down.
Biochemistry
Sep 26, 2017
0
284
