A game of pool in the live cell

Cells need to react to environmental changes and maintain a balanced system of signaling cascades within the cell. Proteins outside of the cell, on the cellular surface, inside the cellular membrane, and within the cell orchestrate ...

CRISPR-based tool maps gene function in human cells

UC San Francisco scientists have used a high-throughput CRISPR-based technique to rapidly map the functions of nearly 500 genes in human cells, many of them never before studied in detail.

Secrets of a little-known cancer ally revealed

Human cancers often have a little recognized ally— the increased size and number of a cell's organelles called the nucleolus. The nucleolus is where ribosomes, the cellular protein factories, are made. Ribosomes can also ...

The Archean Ocean as an ideal breeding ground for life

In a project funded by the Austrian Science Fund FWF, the biochemist Markus Keller demonstrated successfully how important metabolic mechanisms were able to develop in cells four billion years ago. His research provides completely ...

New technique switches key biomolecules on and off

A new technique that will allow scientists to determine the effects of turning on and off a set of molecules involved in almost every cellular pathway, determine their downstream effects, and uncover new drug targets has ...

New procedure allows long-term culturing of adult stem cells

A new procedure developed at Massachusetts General Hospital (MGH) may revolutionize the culturing of adult stem cells. In their report that has been published online prior to its appearance in the August 6 issue of Cell Stem ...

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