Finding the proteins that unpack DNA

A new method allows researchers to systematically identify specialized proteins that unpack DNA inside the nucleus of a cell, making the usually dense DNA more accessible for gene expression and other functions. The method, ...

Molecular brake on human cell division prevents cancer

Researchers at Karolinska Institutet, Sweden, and the University of Sussex, England, have discovered that the process of copying DNA generates a brake signal that stalls cell division. This molecular brake ensures that the ...

DNA replication in HPV

A pair of researchers from the University of Delaware Department of Medical and Molecular Sciences are investigating genetic variations in DNA replication of human papillomaviruses (HPV) and its correlation with HPV-related ...

Researchers build DNA replication in a model synthetic cell

Researchers at Delft University of Technology, in collaboration with colleagues at the Autonomous University of Madrid, have created an artificial DNA blueprint for the replication of DNA in a cell-like structure. Creating ...

Mutating Ebola's key protein may stop replication

Researchers may be able to stop the replication of Ebola virus by mutating its most important protein, according to a paper published in the Journal of Biological Chemistry.

Scientists unravel mysteries of DNA replication in corn

DNA replication is among life's most important processes, providing a way for an organism's genetic material to be reproduced so it can be passed from cell to cell. For the first time, scientists have characterized that process ...

How does a cell maintain its identity during replication?

Prior to cell division, chromosomes are seemingly a jumbled mess. During cell division, parent cell chromosomes and their duplicates sort themselves out by condensing, becoming thousands of times more compact than at any ...

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