The RNA editing protein ADAR1 was first discovered several decades ago. Now, scientists at The Wistar Institute have identified a new function for the protein: It stops cells that have been exposed to stressors such as ultraviolet ...
Cell & Microbiology
Apr 24, 2017
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Cambridge scientists have identified two crucial genetic factors needed to produce specialized root organs that can accommodate nitrogen-fixing bacteria in legumes such as peas and beans.
Molecular & Computational biology
Feb 1, 2024
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23
Cells usually self-destruct when irreparable glitches occur in their DNA. Programmed cell death, or apoptosis, helps insure that cells with damaged DNA do not grow and replicate to produce more mutated cells. Apoptosis thereby ...
Biotechnology
Mar 26, 2014
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(Phys.org) —A team from The University of Manchester – part of the Manchester Cancer Research Centre - have found a new method to more efficiently manufacture a chemical used to monitor cancer cells.
Biochemistry
Apr 24, 2014
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When the body machinery that kills off hundreds of millions of cells a day fails, inflammation and sickness are often not far behind.
Cell & Microbiology
Mar 21, 2023
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8
Cancer researchers of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, Germany, have gained new insights into how cells react to DNA damage. Dr. Michael Stilmann, Dr. Michael Hinz and Professor Claus Scheidereit ...
Cell & Microbiology
Nov 16, 2009
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0
Researchers at the Lomonosov Moscow State University have described the molecular mechanisms of post-translational modifications of caspases, a family of proteolytic enzymes, and how they function during apoptosis, the process ...
Biochemistry
Mar 21, 2017
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10
Programmed cell death, or apoptosis, plays a central role in the maintenance of human health by providing a line of defense against unrestricted cell growth that occurs in many cancers and AIDS as well as in neurodegenerative ...
Cell & Microbiology
Oct 4, 2016
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0
Caspase-2, an initiator caspase, plays a critical role in programmed cell death in response to certain cellular stresses. Its activation is facilitated by the PIDDosome, a multi-protein complex that assembles under conditions ...
Cell & Microbiology
Aug 26, 2024
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3
Using liverwort (Marchantia polymorpha) as a model, researchers led by Prof. Li Hongju from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences have explored the molecular mechanism of sperm ...
Plants & Animals
Jun 3, 2024
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