CRISPR tagging improves accuracy of model cells grown from stem cells
A team of biomedical engineers at Duke University has created a new way to turn stem cells into a desired cell type by mastering the language of gene regulatory networks.
A team of biomedical engineers at Duke University has created a new way to turn stem cells into a desired cell type by mastering the language of gene regulatory networks.
Biotechnology
Dec 1, 2020
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29
In situ sequencing enables gene activity inside body tissues to be depicted in microscope images. To facilitate interpretation of the vast quantities of information generated, Uppsala University researchers have now developed ...
Molecular & Computational biology
Oct 19, 2020
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14
Viral and bacterial pathogens wield pathogenic or virulent proteins that interact with high-value targets inside human cells, attacking what is known as the host interactome. The host interactome is the network map of all ...
Cell & Microbiology
Sep 23, 2020
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6
Using an artificial intelligence (AI) cell classification technique, Northwestern Medicine investigators found that viruses can control structural and genetic polarity inside the cell nucleus. The findings, published in Nature, ...
Cell & Microbiology
Sep 10, 2020
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39
The genes regulating pluripotent stem cells in mammals are surprisingly similar across 48 species, Kyoto University researchers report in the journal Genome Biology and Evolution. The study also shows that differences among ...
Evolution
Sep 7, 2020
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88
Computer systems that emulate key aspects of human problem solving are commonly referred to as artificial intelligence (AI). This field has seen massive progress over the last years. Most notably, deep learning enabled groundbreaking ...
Biotechnology
Aug 4, 2020
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31
Evolution seems to be an unpredictable process. However, predicting the constraints of evolution is possible. Researchers from AMOLF and the French ESPCI have demonstrated this using their mathematical method, followed by ...
Evolution
Jun 25, 2020
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5
Symmetry and asymmetry are fundamental properties of nature. Seen from above, butterflies have left-right symmetry, while male fiddler crabs show dramatic asymmetry. This is also the case for the fundamental units of life: ...
Cell & Microbiology
Jun 25, 2020
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73
For the past several years, Lawrence Livermore National Laboratory (LLNL) scientists and engineers have made significant progress in development of a three-dimensional "brain-on-a-chip" device capable of recording neural ...
Molecular & Computational biology
Jun 15, 2020
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72
In medicine and biology, there is great interest in efficient and inexpensive methods for identifying and separating different cell types, for example for medical diagnostics or for regenerative therapies using stem cells. ...
Cell & Microbiology
May 26, 2020
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17