How jellyfish regenerate functional tentacles in days

At about the size of a pinkie nail, the jellyfish species Cladonema can regenerate an amputated tentacle in two to three days—but how? Regenerating functional tissue across species, including salamanders and insects, relies ...

Review: PROTACs targeting epigenetic proteins

The field of epigenetics focuses on alterations in gene function that are inherited without changes in the DNA sequence, including histone modifications, post-translational modifications of amino acids, and covalent modifications ...

Study finds a thyroxine derivative enhances brain drug delivery

A new study from the University of Eastern Finland shows that the delivery of drugs into the brain, and especially into glial cells, can be enhanced with prodrugs that temporarily incorporate thyroxine or a thyroxine-like ...

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