UC San Francisco scientists have used a high-throughput CRISPR-based technique to rapidly map the functions of nearly 500 genes in human cells, many of them never before studied in detail.
Biotechnology
Jul 20, 2018
0
409
Damage to DNA is a daily occurrence but one that human cells have evolved to manage. Now, in a new paper published in Nature Structural & Molecular Biology, Mayo researchers have determined how one DNA repair protein gets ...
Cell & Microbiology
Jul 2, 2018
0
39
For bacteria facing a dose of antibiotics, timing might be the key to evading destruction. In a series of experiments, Princeton researchers found that cells that repaired DNA damaged by antibiotics before resuming growth ...
Cell & Microbiology
Jun 29, 2018
0
113
Almost every cell in the human body, from beating heart cells to bacteria-gobbling immune cells, is powered by chemical energy produced by specialized organelles called mitochondria. The process of energy generation creates ...
Cell & Microbiology
May 3, 2018
0
17
New research by scientists shows that when cellular barriers are exposed to metal nanoparticles, cellular messengers are released that may cause damage to the DNA of developing brain cells. The discovery may have implications ...
Bio & Medicine
Apr 4, 2018
0
30
A groundbreaking and surprising discovery provides a major conceptual change of what is most important to cells: the fidelity of the DNA transcription process - accurately copying the DNA message into RNA, the precursor to ...
Cell & Microbiology
Oct 4, 2017
0
12
Is it better to do a task quickly and make mistakes, or to do it slowly but perfectly? When it comes to deciding how to fix breaks in DNA, cells face the same choice between two major repair pathways. The decision matters, ...
Cell & Microbiology
Sep 20, 2017
0
249
To fight infections cells in the immune system play a dangerous game with their own genes. Damaging genes allows B cells to make antibodies that are specifically equipped to target to specific causes of illness, but damaging ...
Cell & Microbiology
Sep 13, 2017
0
2
All cells are confronted with DNA damage, for example by exposure of the skin to UV rays, chemical byproducts of nerve cells consuming sugar, or immune cells destroying bacteria. If these DNA lesions are not - or badly - ...
Cell & Microbiology
Jun 13, 2017
0
183
Scientists at the Francis Crick Institute have made a surprising discovery about the Vaccinia virus, a large DNA virus belonging to the pox family that was used as the vaccine to eradicate smallpox.
Cell & Microbiology
May 3, 2017
0
197
