New protein gel for tissue regeneration

The human body can repair a lot of tissue damage itself. But sometimes, for instance in case of operations of wounds, it needs help. In her doctoral research, Gosia Wlodarczyk-Biegun developed a protein polymer that provides ...

One, two, four, eight – lessons from dividing cells

The IMCB was established in 1987 at the National University of Singapore before becoming an autonomous research institute of A*STAR and moving to Biopolis in 2004. The IMCB strives to maintain the scientific excellence of ...

DNA research offers clues on cell mutation

A team of researchers from Colorado State University has been studying DNA damage in living cells to learn more about how genetic abnormalities arise. It has long been known that DNA molecules in every cell get constantly ...

Packaging and unpacking of the genome

DNA represents a dynamic form of information, balancing efficient storage and access requirements. Packaging approximately 1.8m of DNA into something as small as a cell nucleus is no mean feat, but unpacking it again to access ...

DNA strands often 'wiggle' as part of genetic repair

Sometimes, the molecules that make up life exhibit strange behavior. For instance, in simple organisms such as yeast, when genetic material becomes damaged, the affected DNA strands increase their motion, waving about inside ...

Controls of specialization unraveled

Two phases of the cell cycle of human embryonic stem cells have been shown, for the first time, to actively employ pathways that maintain pluripotency—the potential to develop into almost any type of cell in the body.

A barrier against brain stem cell aging

Neural stem cells generate new neurons throughout life in the mammalian brain. However, with advancing age the potential for regeneration in the brain dramatically declines. Scientists of the University of Zurich now identified ...

A novel DNA damage alarm

How does our body keep its DNA intact? Researchers at Erasmus MC have just found a new piece of this puzzle. They discovered a novel alarm that cells use to signal DNA damage. "We already knew that DNA damage triggers an ...

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