(PhysOrg.com) -- Researchers have achieved a feat drug developers had thought difficult, if not impossible, discovering a compound that blocks the functioning of a key developmental protein by binding to an “undruggable” ...
Jan 19, 2009
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(Phys.org) —A rare tree found in Malaysia and Borneo holds the secret to greener chemical production, according to researchers from the Research School of Chemistry.
Biochemistry
Jun 3, 2013
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A new study shows that it is possible to use an imaging technique called cryo-electron microscopy (cryo-EM) to view, in atomic detail, the binding of a potential small molecule drug to a key protein in cancer cells. The cryo-EM ...
Biochemistry
Jan 29, 2016
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Investigators led by Neil Kelleher, Ph.D., professor of Medicine in the Division of Hematology and Oncology and of Biochemistry and Molecular Genetics, have developed an automated technique for imaging and identifying proteoforms ...
Biotechnology
Nov 10, 2023
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Curcumin, a natural molecule related to turmeric, has been used to treat cancer patients in cancer clinical studies. While it has documented antitumor effects, challenges involving its chemistry have caused drug development ...
Biochemistry
Oct 27, 2022
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7
Transcription is a cellular process by which genetic information from DNA is copied to messenger RNA for protein production. But anticancer drugs and environmental chemicals can sometimes interrupt this flow of genetic information ...
Biochemistry
Aug 21, 2012
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While investigating the unusual G quadruplex DNA structure (G4), the Simon Elsässer group has developed a more accurate method for mapping these structures in the genome. G4 CUT&Tag revealed numerous G4s in the human and ...
Biotechnology
Dec 6, 2021
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A Victoria University of Wellington research team has developed an exciting new lead in the search for cancer treatments, creating alternative versions in the laboratory of a rare natural compound that targets some types ...
Biochemistry
Aug 21, 2019
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Cell-to-cell contacts are necessary for the survival of human cells under protein-damaging conditions and stress. This was one of the conclusions made by a research team working under the leadership of Lea Sistonen, Professor ...
Cell & Microbiology
Jan 16, 2020
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5
A recent study by scientists from the Agency for Science, Technology and Research (A*STAR) is the first to report on the use of fluorescent molecular rotors for cancer drug development. The study was published on 30 April ...
Biochemistry
Jul 1, 2014
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