The molecular tool CRISPR-Cas9 can be used to treat inherited blood disorders, but this may cause unintended genetic alterations. A team led by MDC researchers Klaus Rajewsky and Van Trung Chu has now presented an approach ...
Biotechnology
Jun 23, 2022
0
37
The organization of the human genome relies on physics of different states of matter—such as liquid and solid—a team of scientists has discovered. The findings, which reveal how the physical nature of the genome changes ...
General Physics
Jun 2, 2021
0
24
Researchers have discovered a new set of signals that cells send and receive to prompt one type of fat cell to convert fat into heat. The signaling pathway, discovered in mice, has potential implications for activating this ...
Cell & Microbiology
Jun 12, 2020
0
215
A key epigenetic mark can block the binding of an important gene regulatory protein, and therefore prohibit the gene from being turned off, a new UNSW study in CRISPR-modified mice—published this month in Nature Communications—has ...
Biotechnology
May 25, 2020
0
380
A protein known to help cells defend against infection also regulates the form and function of mitochondria, according to a new paper in Nature Communications.
Cell & Microbiology
Mar 3, 2020
0
501
If we really want to know how our body's cells work—or don't work, in the case of disease—we might need to look beyond their genes and even beyond the proteins they are made of. We may need to start going through the ...
Biotechnology
Oct 22, 2018
0
66
A research project that began 20 years ago with an interest in how lithium treats mood disorders has yielded insights into the progression of blood cancers such as leukemia. The research, which centers on a protein called ...
Biochemistry
Oct 31, 2017
0
25
Chinese scientists used an adapted version of a controversial gene-editing technique to correct a disease-causing mutation in human embryos, a medical first cautiously hailed by other experts Thursday.
Biotechnology
Sep 28, 2017
1
116
Computer models developed by Brown University mathematicians show new details of what happens inside a red blood cell affected by sickle cell disease. The researchers said they hope their models, described in an article in ...
Biochemistry
Jul 28, 2017
0
237
A new color-coding tool is enabling scientists to better track live blood stem cells over time, a key part of understanding how blood disorders and cancers like leukemia arise, report researchers in Boston Children's Hospital's ...
Cell & Microbiology
Nov 22, 2016
0
436
