Bacterium from coal mine fire could aid drug targeting

Chemists scouring Appalachia for exotic microorganisms that could yield blockbuster drugs have reported a unique find from the smoldering remains of a coal mine fire that's burned for nearly a decade in southeastern Kentucky.

How maize makes an antibiotic cocktail

Maize (Zea mays) produces a plethora of antibiotics called zealexins. Even though scientists have identified at least 15 zealexins, they suspect there are even more to find. Zealexins are produced in every corn variety and ...

Moulds and plants share similar ways in alkaloid biosynthesis

The fungus Aspergillus fumigatus produces a group of previously unknown natural products. With reference to plant isoquinoline alkaloids, these substances have been named fumisoquins. Researchers from Jena (Germany) discovered ...

Expanding the biosynthetic pathway via retrobiosynthesis

KAIST metabolic engineers present the bio-based production of multiple short-chain primary amines that have a wide range of applications in chemical industries for the first time. The research team led by Distinguished Professor ...

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