New research from the University of Wisconsin–Madison decodes the evolutionary pathway of regulatory proteins, the molecules that help control gene expression.
Evolution
Mar 29, 2024
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162
Mycophenolic acid (MPA), discovered in 1893, was the first natural antibiotic to be isolated and crystallized in human history. Today, this fungal metabolite has been developed into multiple first-line immunosuppressive drugs ...
Biochemistry
Jun 21, 2019
1
1
The fact that nature is an excellent chemist is demonstrated by the abundance of molecules, so-called natural products, which it produces biosynthetically. These natural products are also of central importance to us humans. ...
Biochemistry
May 27, 2022
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317
Maize plants form special compounds derived from indole, the so-called benzoxazinoids. They are considered ecologically important because they act against a wide range of herbivores and reduce their feeding. Benzoxazinoids ...
Evolution
Oct 9, 2023
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243
(PhysOrg.com) -- As the best drugs become increasingly resistant to superbugs, McMaster University researchers have discovered a completely different way of looking for a new antibiotic.
Biochemistry
May 28, 2009
4
0
Scientists have discovered a new chemical process—also known as a biosynthetic pathway—in bacteria which could lead to a new generation of antibiotics being produced and manufactured.
Biochemistry
Nov 26, 2018
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145
Glycosylation—the attachment of sugars to proteins—plays a critical role in both cellular function and in the development of therapeutics, like vaccines.
Cell & Microbiology
Nov 27, 2019
0
57
New research has uncovered the secret of how plants make limonoids, a family of valuable organic chemicals that include bee-friendly insecticides and have potential as anti-cancer drugs.
Biochemistry
Jan 26, 2023
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313
(Phys.org) —Two of the most urgent challenges for scientists are the battles against food shortages and infectious diseases like malaria. Unfortunately, both the herbicides used to protect plants and the anti-infectives ...
Biochemistry
Jan 21, 2014
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0
Fungal infections can be devastating to human health, killing approximately 150 people every hour, resulting in over a million deaths every year, more than malaria and tuberculosis combined.
Cell & Microbiology
Jun 14, 2016
0
97
