Researchers thwart resistant bacteria's strategy

Antibiotic resistant bacteria are experts in evolving new strategies to avoid being killed by antibiotics. One such bacterium is Pseudomonas aeruginosa, which is naturally found in soil and water, but also hospitals, nursing ...

New biocatalytic method eliminates cyanide in nitrile production

If the household cleaner emits a lemon-like odor, this may be due to a nitrile called citronellyl nitrile. These versatile chemical nitrile groups are also used in the manufacture of active pharmaceutical ingredients, superglue ...

Protein study could help researchers develop new antibiotics

A bacterial enzyme called histidine kinase is a promising target for new classes of antibiotics. However, it has been difficult to develop drugs that target this enzyme, because it is a "hydrophobic" protein that loses its ...

Study sheds light on how antibiotic 'Velcro' kills bacteria

A small antibiotic called plectasin uses an innovative mechanism to kill bacteria. By assembling into large structures, plectasin latches onto its target on the bacterial cell surface, similar to how both sides of Velcro ...

Bacterial proteins shed light on antiviral immunity

A unique collaboration between two UT Southwestern Medical Center labs—one that studies bacteria and another that studies viruses—has identified two immune proteins that appear key to fighting infections. The findings, ...

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