Small shining molecules developed by scientists at Linköping University in Sweden can be designed to distinguish between plaque of different proteins in the brain. They may pave the way for better diagnosis of neurodegenerative ...
Biochemistry
Dec 21, 2017
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18
A hallmark of age-related diseases such as Parkinson's disease, type 2 diabetes, or Alzheimer's disease is the abnormal clumping of proteins in cells. In people with these conditions, these protein clumps can result in irregular ...
Biochemistry
Sep 16, 2019
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25
A collaboration led by scientists at Tokyo University of Agriculture and Technology (TUAT), Japan, has discovered a novel amyloid protein from canine mammary tumors. This amyloid protein, α-S1 casein, normally plays a vital ...
Molecular & Computational biology
Jan 24, 2023
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7
Serum amyloid A (SAA) is a family of ancient proteins that can be traced from present-day humans back half a billion years to sea cucumbers and oysters. A new study by researchers from the Boston University Chobanian & Avedisian ...
Molecular & Computational biology
Aug 22, 2023
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19
Massachusetts General Hospital researchers say they have determined how iron contributes to the production of brain-destroying plaques found in Alzheimer's patients.
Biochemistry
Oct 6, 2010
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While amyloid plaques have long been closely associated with mechanisms driving Alzheimer's disease, visualizing how amyloid proteins assemble continues to prove difficult. The nanometer-sized amyloid fibrils are only a fraction ...
Optics & Photonics
Mar 26, 2019
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5
Highly stable polymeric "amyloid" proteins, best known for their role in Alzheimer's disease, have been mostly studied in animals. But a new study on the garden pea publishing July 23, 2020 in the open-access journal PLOS ...
Plants & Animals
Jul 23, 2020
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3
Amyloidosis is a multifaceted disease group caused by deposits of the misfolded "amyloid" protein in various tissues. Amyloid protein is very unique compared to other native proteins in that it has a cross-β-sheet structure, ...
Veterinary medicine
Oct 7, 2021
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4
A team of scientists from the VIB lab of Han Remaut (VIB-VUB) and the lab of Yves Dufrêne at UCL Louvain-La-Neuve collaborated on a study of functional amyloids –protein aggregates with the typical amyloid structure that ...
Biochemistry
Jun 20, 2017
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3
Amyloids are protein aggregates that can form in the body, sometimes leading to diseases such as Alzheimer's. These fibrils can adopt multiple shapes, known as "polymorphs," which complicate our understanding of their role ...
Molecular & Computational biology
Jul 16, 2024
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