Working proteins make good use of frustration
Proteins fold according to a script written in the pattern of their amino acids. But to function properly, some parts must ad-lib.
Proteins fold according to a script written in the pattern of their amino acids. But to function properly, some parts must ad-lib.
Biochemistry
Feb 11, 2019
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49
Though separated by a world of ocean, and unrelated to each other, two fish groups—one in the Arctic, the other in the Antarctic—share a surprising survival strategy: They both have evolved the ability to produce the ...
Biotechnology
Feb 11, 2019
10
210
A new electron microscopy technique that detects the subtle changes in the weight of proteins at the nanoscale—while keeping the sample intact—could open a new pathway for deeper, more comprehensive studies of the basic ...
Nanophysics
Jan 31, 2019
0
178
Proteins have now been designed in the lab to zip together in much the same way that DNA molecules zip up to form a double helix. The technique, whose development was led by University of Washington School of Medicine scientists, ...
Biochemistry
Dec 19, 2018
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108
Today, sugar has a villainous reputation. And while too much of the sweet stuff should be avoided, all living things need sugar to survive. "The biological universe is coated with sugars," said Samuel M. Levi and Qiuhan Li, ...
Materials Science
Dec 17, 2018
0
87
The venom of insects such as wasps and bees is full of compounds that can kill bacteria. Unfortunately, many of these compounds are also toxic for humans, making it impossible to use them as antibiotic drugs.
Biochemistry
Dec 7, 2018
1
608
For the first time, scientists have created, from scratch, self-assembling protein filaments.
Biochemistry
Nov 8, 2018
1
56
Using a novel type of chemical reaction, MIT researchers have shown that they can modify antibiotics in a way that could potentially make them more effective against drug-resistant infections.
Biochemistry
Nov 5, 2018
0
102
DNA is often referred to as the blueprint for life, however scientists have for the first time discovered a microbe that uses two different translations of the DNA code at random. This unexpected finding breaks what was thought ...
Biotechnology
Jun 14, 2018
3
570
MIT chemists have devised a way to rapidly synthesize and screen millions of novel proteins that could be used as drugs against Ebola and other viruses.
Biochemistry
May 21, 2018
2
1353