Search results for CRISPR

Biotechnology Feb 16, 2024

New toolbox allows engineering of genomes without CRISPR

Belgian researchers from VIB-KULeuven Center for Microbiology and VIB-UGent Center for Plant Systems Biology have developed a new toolbox of 16 different short DNA sequences that allow triggering controlled and specific recombination ...

Cell & Microbiology Feb 16, 2024

Newly discovered bacterial defense system functions as self-destruct button

Wageningen researchers have discovered a molecular self-destruct mechanism in a bacterium living on seaweed. With this mechanism the bacteria sacrifice themselves when they are infected, thus protecting their brothers and ...

Cell & Microbiology Feb 15, 2024

Study reveals how cells keep telomerase in check

The natural ends of chromosomes appear alarmingly like broken DNA, much as a snapped spaghetti strand is difficult to distinguish from its intact counterparts. Yet every cell in our bodies must have a way of differentiating ...

Biotechnology Feb 13, 2024

New CRISPR tool accelerates and optimizes genome editing

CRISPR/Cas systems have undergone tremendous advancement in the past decade. These precise genome editing tools have applications ranging from transgenic crop development to gene therapy and beyond. And with their recent ...

Cell & Microbiology Feb 6, 2024

New findings on Bacteroides thetaiotaomicron physiology under bile stress

Researchers from the Würzburg Helmholtz Institute for RNA-based Infection Research (HIRI) deployed CRISPR interference for the first time for the functional characterization of the gut mutualist Bacteroides thetaiotaomicron. ...

Molecular & Computational biology Feb 5, 2024

Shedding light on shadows: Unveiling the impact of low light on tomato disease susceptibility and defense mechanisms

The global challenge of plant disease outbreaks under low light intensities leads to significant crop yield losses, with the mechanisms of low light's impact on plant defense poorly understood. Research has identified high ...

Cell & Microbiology Feb 5, 2024

Preclinical study uncovers two proteins' crucial role in causing cancer cell growth

Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States, have discovered a new cellular mechanism that plays an important role in cancer cells' ability to cause disease. ...

Bio & Medicine Feb 1, 2024

A nanotechnology‐based CRISPR/Cas9 delivery system for genome editing in cancer treatment

In a study published in MedComm—Biomaterials and Applications Professor Changyang Gong and his Ph.D. student Shiyao Zhou elaborate on the mechanism of CRISPR/Cas9 system. The CRISPR/Cas9 system consists of Cas9 protein ...

Biotechnology Feb 1, 2024

Highly targeted CRISPR delivery system advances gene editing in living animals

Most approved gene therapies today, including those involving CRISPR-Cas9, work their magic on cells removed from the body, after which the edited cells are returned to the patient.

Biotechnology Jan 30, 2024

Using CRISPR technology, researchers succeed in growing tomatoes that consume less water without compromising yield

A new discovery by Tel Aviv University has succeeded in cultivating and characterizing tomato varieties with higher water use efficiency without compromising yield. The researchers, employing CRISPR genetic editing technology, ...

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