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Cell & Microbiology Dec 22, 2022

Researchers discover 'Humpty-Dumpty' water-based mechanism of human sex reversal at edge of developmental ambiguity

Researchers from Indiana University School of Medicine have discovered a molecular "clamping" mechanism within a male-specific protein-DNA complex whose mutation causes sex reversal: children with XY chromosomes but female ...

Polymers Nov 15, 2022

Spatiotemporal segregation of chiral supramolecular polymers

In 1848, Louis Pasteur successfully segregated two types of crystals of double sodium-ammonium salt of tartaric acid, which were mirror images of each other. Back then, this was done manually through a painstaking process ...

Molecular & Computational biology Oct 24, 2022

Dietary nucleotide offers new insight for sow breeding

Maternal nutrition status plays a vital role in the growth and development of the major fetal organ systems, and fetal growth is dramatically increased during late gestation while nutrient requirements of sows increase significantly ...

Molecular & Computational biology Oct 17, 2022

'Non-essential' building block proves vital to a healthy protein diet

A "non-essential" amino acid—so-called because the body can make it from other nutrients—can act as a nutritional cue to guide the body's responses to a low-protein diet, a RIKEN-led team has found in a study on fruit fly ...

Biochemistry Sep 2, 2022

New study confirms 'rippled sheet' protein structure predicted in 1953

An unusual protein structure known as a "rippled beta sheet," first predicted in 1953, has now been created in the laboratory and characterized in detail using X-ray crystallography.

Plants & Animals Aug 8, 2022

Apple trees' natural response to virus mirrors genetic modification mechanism, study shows

Apple trees respond to a common viral infection by targeting a gene in the same pathway that genetic scientists are aiming at, find scientists from The University of Manchester. The discovery published in Current Biology ...

Cell & Microbiology Jul 19, 2022

How protein aggregation occurs in cells

Published in the Molecular Cell journal on July 19, a research study out of the Hatters Laboratory showed inappropriate protein aggregation is linked to poor outcomes for cell health and survival—especially in neurons in ...

Biochemistry Jun 27, 2022

New research transforms glucose transporter proteins to water-soluble form

All cell membranes in the human body have embedded proteins that serve as sensors, messengers or as a means of transporting and regulating substances going in and out of the cell. Transport proteins in particular are poorly ...

Molecular & Computational biology Jun 8, 2022

Do proteins remember?

A study integrating biological ideas and new computer science tools has uncovered novel associations between genetic coding and protein structure, which could potentially change the way we think about protein production in ...

Biochemistry May 18, 2022

Enzyme breaks down PET plastic in record time

Plastic bottles, punnets, wrap—lightweight packaging made of PET plastic becomes a problem if it is not recycled. Scientists at Leipzig University have now discovered a highly efficient enzyme that degrades PET in record ...

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