Search results for intermediate compounds

Analytical Chemistry Jan 16, 2024

Researchers achieve electrosynthesis of LiTFSI and N-containing analogs via looped Li-N₂ battery

Lithium bis(trifluoromethanesulfonyl)imide, commonly known as LiTFSI, and its analogs, are critical electrolytes for lithium batteries and solar cells. However, the commercialization of LiTFSI through thermal chemical synthesis ...

Analytical Chemistry Jan 16, 2024

One-step synthesis of the most common, yet highly intricate, antibiotic molecular scaffold

While we appear to live in a world of plenty, behind the scenes, sourcing sufficient amounts of key ingredients can be challenging. For example, the synthesis of certain antibiotics, beta-lactam antibiotics, requires certain ...

Analytical Chemistry Jan 11, 2024

New catalytic technique creates key component of incontinence drug in less time

A research group at Nagoya University in Japan has developed a new catalyst that promises to revolutionize the asymmetric synthesis of pharmaceuticals called chiral macrocyclic dilithium(I) salt. It overcomes the lack of ...

Analytical Chemistry Jan 10, 2024

Researchers report successful synthesis of specific chiral molecules using rearrangements of simple hydrocarbons

In nature, organic molecules are either left- or right-handed, but synthesizing molecules with a specific "handedness" in a lab is hard to do. Make a drug or enzyme with the wrong "handedness," and it just won't work. Now ...

Analytical Chemistry Jan 10, 2024

Scientists achieve real-time capture of ionization process and subsequent structural changes

Ions are everywhere, from our daily surroundings to the cosmic expanse. As common table salt (NaCl) dissolves into sodium (Na+) and chloride (Cl-) ions in water, it imparts a salty taste. Once absorbed by the body, these ...

Cell & Microbiology Jan 2, 2024

First step towards synthetic carbon dioxide fixation in living cells

Synthetic biology offers the opportunity to build biochemical pathways for the capture and conversion of carbon dioxide (CO2). Researchers at the Max-Planck-Institute for Terrestrial Microbiology have developed a synthetic ...

Biochemistry Dec 29, 2023

Breakthrough in nitrile activation is promising pathway for anticancer precursor synthesis

A research team, affiliated with UNIST has unveiled a novel method to produce a selective anticancer precursor substance that targets and eliminates cancer cells. This groundbreaking method, previously existing only in theory, ...

Biochemistry Dec 28, 2023

Oral peptides: A new era in drug development

For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy. Traditional small molecules often struggle to bind to proteins with flat surfaces or require ...

Biochemistry Dec 21, 2023

Thianthrenium chemistry allows reactivity switch of a nucleophilic amino acid into a versatile intermediate

Chemical diversification of proteins is an important concept in the study of biological processes and the complex structures of the proteins themselves. Researchers from the Max Planck Society have now published their fascinating ...

Plants & Animals Dec 13, 2023

Scientists identify biosynthetic pathway of chemotherapeutic derived from yew trees

Researchers from the Max Planck Institute of Molecular Plant Physiology have unraveled the biosynthetic pathway of paclitaxel in yew plants, a chemotherapeutic for cancer treatment. This discovery might facilitate the production ...

page 5 from 40