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Biotechnology Jun 16, 2022

Nanochannels light the way toward new medicine

To develop new drugs and vaccines, detailed knowledge about nature's smallest biological building blocks—biomolecules—is required. Researchers at Chalmers University of Technology, Sweden, are now presenting a groundbreaking ...

Molecular & Computational biology Jun 14, 2022

Fluorescence microscopy shows how living cells form vesicles to transport cargo like growth factors

Cells have a clever way to transport cargos like growth factors across the cell membrane and into the cell. It is called clathrin-mediated endocytosis. Molecules of the protein clathrin gather on the inside of the cell membrane, ...

Biotechnology Jun 9, 2022

Multi-scale imaging confirms protein's role in neuronal structure, dynamics

Protein structures are typically determined by studying them in their purified form, outside the busy inner workings of the cell, and because of this, their biological relevance is often called into question. In a new study ...

Cell & Microbiology Jun 9, 2022

Scientists uncover clues about the generation of nanomachines in Salmonella

Researchers at the University of Liverpool have captured a clear view of the generation process of "protein machinery" that plays a key role in the colonization of pathogenic Salmonella bacteria.

Cell & Microbiology May 27, 2022

Benchmarking transcriptomics integration methods for transcript distribution prediction and cell type deconvolution

In a study published in Nature Methods, a research team led by Prof. Qu Kun from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences has benchmarked 16 spatial and single-cell transcriptomics ...

Biochemistry May 26, 2022

Three chaperones coordinate the breakup of amyloid fibrils in yeast

In a finding that has important ramifications for neurodegenerative disorders such as Alzheimer's disease, RIKEN researchers have discovered how three chaperone molecules in yeast cells work together to break up beta-sheet-rich ...

Biochemistry May 18, 2022

Researchers magnify hidden biological structures by combining SRS and expansion microscopy

A research team from Carnegie Mellon University and Columbia have combined two emerging imaging technologies to better view a wide range of biomolecules, including proteins, lipids and DNA, at the nanoscale. Their technique, ...

Cell & Microbiology May 4, 2022

Reactive microscopy with MicroMator software

Microscopic imaging analysis is a crucial component of biochemistry and medicine, with significant progress in accuracy and speed made due to machine learning methods and improved computation. These technical advances can ...

Nanophysics Apr 28, 2022

Harnessing the powers of light to operate computers

It is said that light is the source of life, and in the near future, it will possibly form the basis of our everyday personal computing needs too. Recently, researchers from the University of Tsukuba have harnessed specific ...

Biotechnology Apr 28, 2022

Evanescent scattering microscopy: A sharper image for proteins

Proteins may be the most important and varied biomolecules within living systems. These strings of amino acids, assuming complex 3-dimensional forms, are essential for the growth and maintenance of tissue, the initiation ...

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