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Cell & Microbiology Oct 31, 2022

A new protocol for light-sheet live imaging of C. elegans adults

The beauty of live-imaging studies is the specimen is alive, allowing dynamics such as cell division and embryonic development to be recorded over time.

Biochemistry Oct 13, 2022

Lipid expansion microscopy uses 'power of click chemistry'

Lipids—fats—make great walls for cells and organelles because they are water resistant and dynamic. But those same characteristics also make them hard to image using expansion microscopy, a technique that works for magnifying ...

Optics & Photonics Oct 7, 2022

Medical optical imaging using the world's first 'ultrasound-induced tissue transparency' technology

A joint research team from DGIST led by Professors Jin Ho Chang and Jae Youn Hwang of the Department of Electrical Engineering and Computer Science has developed the world's first laser scanning microscopy technology that ...

General Physics Sep 22, 2022

Detailed insight into friction: How objects start to slide

Chemists and physicists at the University of Amsterdam shed light on a crucial aspect of friction: how things begin to slide. Using fluorescence microscopy and dedicated fluorescent molecules, they are able to pinpoint how ...

Optics & Photonics Sep 21, 2022

New endoscope uses bendable GRIN lens for 3D microscopy

Researchers have created a flexible needle-like endoscopic imaging probe that can acquire 3D microscopic images of tissue. The bendability is possible thanks to a new flexible graded index (GRIN) lens developed by the researchers.

Cell & Microbiology Sep 19, 2022

Cilia in 3D: Miniature 'train station' discovered

Cilia are small hair-like organelles that extend from cells and perform many functions, including motility and signaling. Researchers have now revealed that cilia have a specialized transport hub at their base, where trains ...

Optics & Photonics Sep 16, 2022

A new holographic microscope allows scientists to see through the skull and image the mouse brain

Researchers led by Associate Director Choi Wonshik of the Center for Molecular Spectroscopy and Dynamics within the Institute for Basic Science, Professor Kim Moonseok of The Catholic University of Korea, and Professor Choi ...

Biochemistry Sep 14, 2022

Dense and permeable: Molecular organization of tight junctions decoded

They seal epithelial cells and, under certain conditions, allow the passage of ions and water: Tight junctions form a paracellular barrier in tissues and their dysfunction is associated with diseases. Although their molecular ...

Optics & Photonics Sep 13, 2022

High-performance 937-nm laser lets scientists see deeper with lower power

Two-photon microscopy (2PM) plays a reliably efficient role in noninvasive deep-tissue imaging in biomedical investigation. Since the invention of the two-photon microscope at the end of the 20th century, there has been a ...

Cell & Microbiology Sep 8, 2022

Intelligent microscopes for detecting rare biological events

Imagine you're a Ph.D. student with a fluorescent microscope and a sample of live bacteria. What's the best way use these resources to obtain detailed observations of bacterial division from the sample?

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