Search results for CRISPR-Cas9

Evolution Aug 10, 2022

Nearly a hundred genes have been lost during the woolly mammoth's evolution

A new study shows that 87 genes have been affected by deletions or short insertions during the course of the mammoth's evolution. The researchers note that their findings have implications for international efforts to resurrect ...

Biotechnology Aug 9, 2022

Gene editing via CRISPR/Cas9 can lead to cell toxicity and genome instability

CRISPR/Cas9 is a precise gene editing technique whose development by Jennifer A. Doudna and Emmanuelle Charpentier was recognized with the 2020 Nobel Prize in Chemistry. Commonly known as "genetic scissors," CRISPR allows ...

Molecular & Computational biology Aug 8, 2022

The novel leucine-rich repeat receptor-like kinase MRK1 regulates resistance to multiple stresses in tomato

Tomato (Solanum lycopersicum L.) is an economically important vegetable crop worldwide, and its production is threatened by temperature fluctuations and pathogen attacks, causing severe crop losses. In recent work published ...

Cell & Microbiology Aug 8, 2022

Enhancers cooperate to regulate master transcription factors for sound receptor hair cell development

A study published in PNAS on Aug. 5 reveals the genome-wide chromatin accessibility of neonatal cochlear hair cells (HCs) and has identified two previously unknown Atoh1 enhancers. This study demonstrates that three Atoh1 ...

Molecular & Computational biology Aug 4, 2022

Endogenous ceramide phosphoethanolamine modulates circadian rhythm and longevity in Drosophila

The circadian clock entrains rhythmic patterns in behavioral and physiological processes to temporally coordinate systemic metabolism with the rising and setting of the sun. In previous investigation on human subjects, sphingomyelins ...

Cell & Microbiology Jul 21, 2022

How the zebrafish repairs a broken heart

An MDC research team led by Jan Philipp Junker and Daniela Panáková has found that zebrafish can regenerate heart tissue after injury. Connective tissue cells play an important role in the process by temporarily entering ...

Plants & Animals Jul 21, 2022

Modified method helps to induce transgenic hairy roots from stem of tung tree seedling

Tung tree is an oil-bearing woody plant species in the Euphorbiaceae family. The oil extracted from tung tree seeds, called tung oil, is an excellent dry oil that is resistant to heat, cold, acid, alkali and corrosion, and ...

Molecular & Computational biology Jul 19, 2022

Researchers discover wheat yield-enhancing gene

Researchers led by Dr. Jiao Yuling from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences, together with collaborators from Peking University, have found that gene editing of an APETALA2/ethylene ...

Biotechnology Jul 18, 2022

Synthetic tools conduct messages from station to station in DNA

Rice University researchers have demonstrated that CRISPR-Cas9, increasingly famous as a gene-editing tool, can be employed in powerful additional ways in human cells.

Plants & Animals Jul 14, 2022

Cooperative mechanisms of duplicated genes in male differentiation in carp

Polyploidy or whole-genome duplication (WGD) provides extra substrates for genomic evolution and is thus considered as an important driving force for genetic diversity, trait innovation, and ecological adaption. Despite extensive ...

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