Search results for CRISPR-Cas9

Cell & Microbiology Jul 11, 2022

Hidden genes may be tapped for new antibiotics

Silents are potentially golden in the search for antibiotics to slow the ongoing crisis of resistance in the treatment of disease.

Ecology Jul 8, 2022

Genetically-enhanced biocontrols could help fight large invasive mammals

Invasive alien mammals can have catastrophic impacts on native flora and fauna, causing species extinctions and driving profound environmental change. Classical control methods such as poison baiting, trapping, or hunting ...

Cell & Microbiology Jul 6, 2022

A potential danger of CRISPR gene editing—and why base editing may be safer

Gene therapy using CRISPR/Cas9 gene editing is currently in clinical trials around the world for a variety of diseases. A report from Boston Children's Hospital, published June 27 in Nature Communications, warns of a potential, ...

Biotechnology Jul 1, 2022

'Soft' CRISPR may offer a new fix for genetic defects

Curing debilitating genetic diseases is one of the great challenges of modern medicine. During the past decade, development of CRISPR technologies and advancements in genetics research brought new hope for patients and their ...

Evolution Jun 30, 2022

Borrowed gene helps maize adapt to high elevations, cold temperatures

Researchers at North Carolina State University show that an important gene in maize called HPC1 modulates certain chemical processes that contribute to flowering time, and has its origins in "teosinte mexicana," a precursor ...

Plants & Animals Jun 30, 2022

Annual animal research numbers published

The Francis Crick Institute has published its 2021 statistics on animal research, as part of its commitment to openness about animal research.

Plants & Animals Jun 27, 2022

Gene fusion as an important mechanism to generate new genes in Oryza genomes

Events of gene fusion have been reported in several organisms. However, the role of gene fusion as part of new gene origination remains unknown. Evolutionary new genes, fused from more than two parental genes, can duck out ...

Bio & Medicine Jun 23, 2022

Lipid nanoparticles carry gene-editing cancer drugs past tumor defenses

As they grow, solid tumors surround themselves with a thick, hard-to-penetrate wall of molecular defenses. Getting drugs past that barricade is notoriously difficult. Now, scientists at UT Southwestern have developed nanoparticles ...

Plants & Animals Jun 23, 2022

Unveiling the mechanism by which light regulates rice flowering time

Light affects most organisms. In plants, many behaviors and functions are determined by the length of light and dark cycles, including flowering. In the most recent publication of The Proceedings of the National Academy of ...

Biotechnology Jun 23, 2022

A fine-tuned gene editor that minimizes adverse consequences

The molecular tool CRISPR-Cas9 can be used to treat inherited blood disorders, but this may cause unintended genetic alterations. A team led by MDC researchers Klaus Rajewsky and Van Trung Chu has now presented an approach ...

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