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Cell & Microbiology Feb 1, 2024

New research shows that the arrangement of bacteria in biofilms affects their sensitivity to antibiotics

Bacteria are traditionally imagined as single-cell organisms, spread out sparsely over surfaces or suspended in liquids, but in many environments the true bacterial mode of growth is in sticky clusters called biofilms.

Cell & Microbiology Jan 24, 2024

Innovative microscopy technique reveals secrets of lipid synthesis inside cells

South Korean researchers led by Director Cho Minhaeng at the IBS Center for Molecular Spectroscopy and Dynamics (IBS CMSD) have made a pivotal discovery in the field of cellular microscopy. The team has successfully developed ...

Optics & Photonics Jan 23, 2024

Rolling Fourier ring correlation method maps local quality at super-resolution scale

Super-resolution (SR) fluorescence microscopy, through the use of fluorescent probes and specific excitation and emission procedures, surpasses the diffraction limit of resolution (200~300 nm) that was once a barrier.

Bio & Medicine Jan 15, 2024

A single dose of urea-powered nanorobots reduces bladder tumors by 90% in mouse study

Bladder cancer has one of the highest incidence rates in the world and ranks as the fourth most common tumor in men. Despite its relatively low mortality rate, nearly half of bladder tumors resurface within 5 years, requiring ...

Biotechnology Jan 10, 2024

Noninvasive technique reveals how cells' gene expression changes over time

Sequencing all of the RNA in a cell can reveal a great deal of information about that cell's function and what it is doing at a given point in time. However, the sequencing process destroys the cell, making it difficult to ...

Cell & Microbiology Jan 8, 2024

Researchers discover important membrane transport mechanism in pathogenic bacteria

Some bacterial membrane transporters work almost like freight elevators to transport substances through the cell membrane into the interior of the cell. The transporter itself spans the bacterial membrane. Like a forklift, ...

Cell & Microbiology Dec 21, 2023

Location, location, location: Research reveals the hidden power of intracellular neighborhoods

New findings published in Molecular Cell provide details about the hidden organization of the cytoplasm—the soup of liquid, organelles, proteins, and other molecules inside a cell. The research shows it makes a big difference ...

Cell & Microbiology Dec 11, 2023

Integrating AI with super-resolution microscopy for advancements in cellular biology

In 2014, the Nobel Prize in Chemistry celebrated the breakthroughs in super-resolution microscopy, a technology that allows us to capture highly detailed images of small parts of cells using fluorescent microscopy. Despite ...

Molecular & Computational biology Dec 8, 2023

Structure of a central component of the human immune system revealed

A central component of the human immune system, the NLRP3 inflammasome plays an important role in fighting off infections. However, its chronic activation is also implicated in a variety of common diseases, such as Alzheimer's, ...

Optics & Photonics Dec 4, 2023

Q&A: Unveiling a new era of imaging—engineers lead breakthrough microscopy techniques

When microscopes struggle to pick up faint signals, it's like trying to spot subtle details in a painting or photograph without your glasses. For researchers, this makes it difficult to catch the small things happening in ...

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