Search results for bone regeneration

Biotechnology Feb 11, 2019

Injectable sponge-like gel enhances the quantity and quality of T-cells

Bone marrow transplants, also known as hematopoietic stem cell transplants, are life-saving treatments for aggressive diseases, such as leukemia and multiple myeloma, and infections such as HIV. The procedure entails infusion ...

Materials Science Feb 7, 2019

Bioplotting bone-mimetic 3-D tissue scaffolds with osteogenic effects

In bone tissue engineering (BTE), 3-D printing is a reliable and customizable method used to repair bone defects by producing biomimetic tissue scaffolds. In a recent study published online on Tissue Engineering Part A (Mary ...

Plants & Animals Jan 4, 2019

The Prickle1 gene regulates the differentiation of frontal bone osteoblasts in a new animal model

A mechanically compromised skull can result from enlarged fontanelles and smaller frontal bones due to defective migration and differentiation of osteoblasts in the skull primordia (developing skull). The Wnt/Planar cell ...

Nanomaterials Jan 3, 2019

Glassy carbon microneedles: A new transdermal drug delivery device

Microneedles are designed to infuse medications transdermally (through the skin) and relatively painlessly during clinical applications. In a recent study, Richa Mishra and her colleagues developed a new technique to convert ...

Materials Science Dec 13, 2018

Enhanced osteogenic activity of pre-osteoblasts on surface-modified 3-D printed scaffolds

Materials such as poly(ε-caprolactone) are used as scaffolds in bone tissue engineering, but their inherent hydrophobicity and surface smoothness can impair cell attachment, proliferation and differentiation in the lab, or ...

Cell & Microbiology Dec 5, 2018

Mechanism for turning skin cells into blood stem cells uncovered

Researchers have succeeded in converting human skin cells into blood stem cells in an international collaboration project. "This is a first step on the way to generating fully functional blood stem cells in a petri dish which, ...

Materials Science Nov 21, 2018

A hydrogel that adheres firmly to cartilage and meniscus

EPFL researchers have developed a hydrogel – made up of nearly 90% water – that naturally adheres to soft tissue like cartilage and the meniscus. If the hydrogel carries repair cells, it could help damaged tissue to heal.

Bio & Medicine Nov 12, 2018

Developing a 3-D collagen model to test magnetic-assisted osteogenesis in vitro

The cellular and molecular mechanisms of magnetic stimulation-based bone regeneration require further understanding at present. To evaluate the phenomenon in the lab, a three-dimensional (3-D) native collagen model was recently ...

Cell & Microbiology Nov 6, 2018

Bioreactor device helps frogs regenerate their legs

A team of scientists designed a device that can induce partial hindlimb regeneration in adult aquatic African clawed frogs (Xenopus laevis) by "kick-starting" tissue repair at the amputation site. Their findings, appearing ...

Biotechnology Oct 30, 2018

Genes behind rapid deer antler growth, hardening identified

Each spring, male deer sprout a new pair of antlers, which are essentially temporary external bones, at a speed unparalleled by the bone growth of other mammals. Now, research led by scientists at the Stanford University ...

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