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Search results for fluorescence microscopy

Biotechnology Aug 7, 2024

Improving resolution and reducing noise in fluorescence microscopy with ensured fidelity

Fluorescence microscopy is a cornerstone of modern biological imaging, allowing scientists to study cells and their processes in real time. However, limitations in resolution and noise levels can hinder the clarity and detail ...

Ecology Aug 2, 2024

Ancient Antarctic microorganisms are aggressive predators

In Antarctica there is a small lake, called Deep Lake, that is so salty it remains ice-free all year round despite temperatures as low as -20°C in winter. Archaea, a unique type of single-celled microorganism, thrive in this ...

Biotechnology Aug 1, 2024

Electrical impedance tomography plus extracellular voltage activation technique simplifies drug screening

When developing new drugs, understanding their effects on ion channels in the body, such as the human ether-a-go-go-related gene (hERG) ion channel found in neurons and heart muscle cells, is critical. Blocking hERG channels ...

Biotechnology Jul 30, 2024

ACE-ing protein detection in single cells

Since the 1950s, researchers have used a famous method invented by Wallace Coulter known as "flow cytometry" to characterize different types of immune cells in research studies and in blood samples from human individuals. ...

Biochemistry Jul 30, 2024

Scientists convert bacteria into efficient cellulose producers

Bacteria produce materials that are of interest to humans, such as cellulose, silk and minerals. The advantage of producing bacteria in this way is that it is sustainable, takes place at room temperature and in water. A disadvantage ...

Cell & Microbiology Jul 23, 2024

Researchers explore a single cell using advanced X-ray imaging techniques

Every plant, animal, and person is a rich microcosm of tiny, specialized cells. These cells are worlds unto themselves, each with their own unique parts and processes that elude the naked eye.

Biochemistry Jul 4, 2024

A closer look at cell toxins: Researchers examine how radionuclides interact with kidney cells

When radionuclides enter our organism, whether by inhalation, ingestion, or through wounds, they pose a potential health risk. Many previous studies on radionuclide exposure have focused mainly on animal experiments. However, ...

Optics & Photonics Jul 2, 2024

Researchers develop low-cost light sheet fluorescence microscope

Three-dimensional (3D) imaging of organs and tissues is vital as it can provide important structural information at the cellular level. 3D imaging enables the accurate visualization of tissues and also helps in the identification ...

Cell & Microbiology Jun 25, 2024

New fluorescent reporting system illuminates accumulation of unfolded proteins in endoplasmic reticulum

The endoplasmic reticulum (ER) is a major organelle responsible for protein folding and trafficking. Protein folding stress in the ER can lead to the accumulation of unfolded or misfolded proteins, known as ER stress, which ...

Optics & Photonics Jun 21, 2024

New physics-informed neural network for universal and high-fidelity resolution enhancement in fluorescence microscopy

To address the limitations of current computational super-resolution microscopy, a team of researchers at Zhejiang University has introduced a novel deep-physics-informed sparsity framework that significantly enhances structural ...

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