A study addressing the complex regulation of HSCs, highlights p21's multifunctional nature beyond cell cycle control. Through the use of p21-tdTomato mice, researchers differentiate between p21-tdT+ and p21-tdT− HSCs.
Billions of our cells die every day to make way for the growth of new ones. Most of these goners are cleaned up by phagocytes—mobile immune cells that migrate where needed to engulf problematic substances. But some dying ...
Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic replication stress. However, a ...
Researchers at University of Tsukuba have made a significant contribution to the understanding of the regeneration of skeletal muscle stem cells, shedding light on the mechanisms underlying muscle aging and regeneration.
A pivotal study sheds light on the evolutionary conservation of stem cell homeostasis in Solanaceae, revealing how receptor compensation mechanisms ensure the continuous and orderly formation of plant organs. This research ...
RIKEN researchers have uncovered how gradual changes in gene-expression patterns drive a cell-fate switch in neural stem cells (NSCs) in mice.
A gentle rumble ran under Ngan Huang's feet as a rocket carrying her research—live, human muscle cells grown on scaffolds fixed on tiny chips—lifted off, climbed, and disappeared into the sky to the International Space Station ...
Current gene therapies to treat sickle cell disease are complex, time-consuming, and are sometimes linked to serious side effects like infertility or blood cancer. To address these challenges, Johns Hopkins researchers have ...
Humanity is on the verge of entering a new era of space exploration, with the Artemis III mission planning to return humans to the moon in 2026, for the first time in 50 years. Not only will Artemis see a woman and a person ...
Using computer-designed proteins, researchers have now shown they are able to direct human stem cells to form new blood vessels in the lab. This milestone in regenerative medicine offers new hope for repairing damaged hearts, ...
