Search results for CRISPR

Biotechnology Jan 22, 2024

CRISPR off-switches: A path towards safer genome engineering?

Using CRISPR, an immune system bacteria use to protect themselves from viruses, scientists have harnessed the power to edit genetic information within cells. In fact, the first CRISPR-based therapeutic was recently approved ...

Biotechnology Jan 16, 2024

Meet pAblo·pCasso: A new leap in CRISPR technologies for next-gen genome engineering

A new CRISPR-Cas toolkit, dubbed "pAblo·pCasso," is set to transform the landscape of bacterial genome editing, offering unprecedented precision and flexibility in genetic engineering. The new technology, developed by researchers ...

Biotechnology Jan 11, 2024

Bioinformatics: Researchers develop a new machine learning approach

To combat viruses, bacteria and other pathogens, synthetic biology offers new technological approaches whose performance is being validated in experiments. Researchers from the Würzburg Helmholtz Institute for RNA-based ...

Biotechnology Jan 11, 2024

Researchers develop prime editors using Cas12a and circular RNAs in human cells

In a study published in Nature Biotechnology, Gao Caixia's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has developed a series of new prime editors based on the Cas12a ...

Plants & Animals Jan 9, 2024

Plant warfare: The crucial function of Nrc proteins in tomato defense mechanisms

In the fascinating world of plant biology, a study recently featured on the cover of The Plant Journal has been turning heads. The research delves into the intricate defense mechanisms of tomatoes against the notorious bacterial ...

Biotechnology Dec 21, 2023

CRISPR/Cas9's role in fine-tuning miRNA expression in tetraploid potatoes

MicroRNAs (miRNAs) play a crucial role in plant gene regulation, with their biogenesis involving complex processes. Fine-tuning miRNAs is a powerful biotechnology strategy that can improve plant performance in the field, ...

Bio & Medicine Dec 15, 2023

Researchers develop new electrochemical chemosensor for fast, effective diagnosis of a lethal pulmonary disease

Patients struggling with some chronic diseases often must wait years for a proper diagnosis. For example, symptoms such as shortness of breath can be attributed to many pulmonary as well as cardiovascular disorders, so patients ...

Cell & Microbiology Dec 14, 2023

A CRISPR pioneer looks back as the first gene-editing therapy is approved

In 2007, Luciano Marraffini struck out on what was then a scientifically lonely path: to understand CRISPR, which had been discovered in bacteria only about a decade before.

Biotechnology Dec 5, 2023

New enzyme allows CRISPR technologies to accurately target almost all human genes

A team of engineers at Duke University have developed a method to broaden the reach of CRISPR technologies. While the original CRISPR system could only target 12.5% of the human genome, the new method expands access to nearly ...

Biotechnology Dec 4, 2023

Researchers characterize translation inhibition in CRISPR-Cas antiviral defense system

A recent study in Science uses bioinformatic analysis as well as biochemical and structural studies to characterize a novel family of effector proteins, named Cami1. The research shows that when a virus attacks a bacterium, ...

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