In the medicine market, most newly introduced drugs and drug candidates show poor water solubility, which prevents their absorption in the body. This, in turn, limits their therapeutic efficiency. Solubilizing agents such ...
Certain molecules bind tightly to the surface of ice, creating a curved interface that can halt further ice growth. Some insects, plants, and sea-dwelling creatures contain protein molecules of this type that act as natural ...
Alzheimer's disease (AD) is one of the biggest global public health challenges. However, the pathogenesis of AD is still unclear.
Intense sunlight damages the chloroplasts that are essential for photosynthesis, and generates toxic products that can lead to cell death. LMU biologists have now identified a signaling pathway which mitigates the effects ...
Living organisms form biological minerals during biomineralization, where inorganic elements can selectively deposit on specific organic macromolecules under precise control. The process can be divided into biocalcification ...
The unicellular parasite that causes sleeping sickness differs from other eukaryotes in the mode of regulation of an essential cellular signaling pathway. This provides a promising point of attack for drug development.
Bacteria, plants, insects and fish use antifreeze proteins to protect themselves from the cold. The proteins block the growth of ice crystals. In a new study, a German-Israeli research team has confirmed that these proteins ...
Early in the course of Alzheimer's disease—long before future patients begin to notice symptoms—neurofibrillary tangles composed of tau protein aggregates begin to form in their brain cells. How toxic these aggregates ...
Most of us don't think about our teeth and bones until one aches or breaks. A team of engineers at Washington University in St. Louis looked deep within collagen fibers to see how the body forms new bone and teeth, seeking ...
Researchers from North Carolina State University have found that diffusion plays an unexpected role in cell differentiation during the early stages of development in the embryos of Drosophila, or fruit flies. Instead of spreading ...
