A research team led by scientists at the Whitehead Institute has described the structure of a key protein complex that helps activate mTORC1, a master growth regulator that enables cells to quickly respond to changing nutrient ...
Cell & Microbiology
Nov 6, 2019
0
73
A team of Whitehead Institute scientists has for the first time revealed the molecular structure of a critical growth regulator bound to its partner proteins, creating a fine-grained view of how they interact to sense nutrient ...
Molecular & Computational biology
Oct 11, 2019
0
157
During embryonic development, stem cells begin to take on specific identities, becoming distinct cell types with specialized characteristics and functions, in order to form the diverse organs and systems in our bodies. Cells ...
Biotechnology
Sep 26, 2019
0
23
Different subpopulations of a plant species can have distinct traits, varying in size, seed count, coloration, and so on. The primary source of this variation is genes: different versions of a gene can lead to different traits. ...
Biotechnology
Nov 20, 2018
0
20
While our genome contains a vast repertoire of genes that are responsible for virtually all of the cellular and developmental processes life requires, it is the complex dance of regulating their expression that is vital for ...
Biotechnology
Dec 15, 2017
0
15
A research team led by Whitehead Institute for Biomedical Research has harnessed metabolomic technologies to unravel the molecular activities of a key protein that can enable plants to withstand a common herbicide. Their ...
Biotechnology
Nov 27, 2017
0
205
The transition from an egg to a developing embryo is one of life's most remarkable transformations. Yet little is known about it. Now Whitehead Institute researchers have deciphered how one aspect—control of the all-important ...
Cell & Microbiology
Jun 15, 2017
0
4
Proteins do most of the work inside the human body, supporting the structure, function, regulation, and repair of organs, tissues and cells. Proteins are synthesized as extended chains of amino acids that must fold into intricate ...
Cell & Microbiology
Feb 23, 2017
1
10
Whitehead Institute researchers have determined how the master transcriptional regulator of the heat shock response, known as heat shock factor 1 (HSF1), is activated and controlled. This insight could lead to treatments ...
Cell & Microbiology
Nov 14, 2016
0
5
A team of Whitehead Institute and Stanford University scientists are redefining what it means to be a prion—a type of protein that can pass heritable traits from cell to cell by its structure instead of by DNA.
Biochemistry
Oct 4, 2016
0
1
