Cell membrane protrusions called blebs that typically signify the end of life for healthy cells do the opposite for melanoma cells, activating processes in these cells that help them to survive and spread, a UT Southwestern ...
Cell & Microbiology
Mar 6, 2023
0
11
UT Southwestern biochemist Zhijian "James" Chen, Ph.D., famously identified the cGAS enzyme pathway that alerts the human immune system to disease-causing invaders like viruses. Since then, researchers have found that cGAS ...
Cell & Microbiology
Mar 1, 2023
0
11
An enzyme called Fic, whose biochemical role was discovered at UT Southwestern more than a dozen years ago, appears to play a crucial part in guiding the cellular response to stress, a new study suggests. The findings, published ...
Cell & Microbiology
Oct 3, 2022
0
69
Using UT Southwestern's Cryo-Electron Microscopy Facility, researchers have captured images of an enzyme for Wnt lipidation, which is pivotal to human development and crucial for Wnt signaling activation. The findings, reported ...
Biochemistry
Aug 16, 2022
0
18
A team led by UT Southwestern researchers has identified how SARS-CoV-2, the virus that causes COVID-19, builds a structure called the RNA cap that's critical for successful viral replication. The finding, published in Nature, ...
Molecular & Computational biology
Aug 10, 2022
0
92
Newly developed artificial intelligence (AI) programs have accurately predicted the role of DNA's regulatory elements and three-dimensional (3D) structure based solely on its raw sequence, according to two recent studies ...
Biotechnology
Aug 8, 2022
0
1110
Using artificial intelligence, UT Southwestern researchers have discovered a new family of sensing genes in enteric bacteria that are linked by structure and probably function, but not genetic sequence. The findings, published ...
Molecular & Computational biology
Jul 2, 2022
0
281
A collaborative study from UT Southwestern scientists has identified a new function for a protein called TAO2 that appears to be key to inhibiting replication of the influenza virus, which sickens millions of individuals ...
Cell & Microbiology
Jun 20, 2022
0
278
Protein complexes that play a critical role in launching an immune response assemble in droplets that form within the liquid environment in cells much like oil droplets in water, UT Southwestern scientists report in a new ...
Cell & Microbiology
Jun 3, 2022
0
35
UT Southwestern researchers have discovered a molecular pathway that allows cells to sense when their lipid supplies become depleted, prompting a flurry of activity that prevents starvation. The findings, reported in Nature, ...
Cell & Microbiology
May 18, 2022
0
75
