Understanding the tens of thousands of proteins that compose the human proteome has emerged as a key challenge of this century, and research efforts to date have already enabled major advances in drug discovery and understanding ...
Biotechnology
Mar 29, 2009
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0
Chemists at Scripps Research have invented an efficient method for making a synthetic version of the plant compound bilobalide, which is naturally produced by gingko trees. It's a significant feat because bilobalide—and ...
Biochemistry
Oct 17, 2019
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87
In a discovery that may further the understanding of diabetes and human longevity, scientists at Scripps Research have found a new biological mechanism of insulin signaling. Their study, involving the roundworm C. elegans, ...
Cell & Microbiology
Feb 25, 2020
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203
"Pluripotent" stem cells—which have the potential to mature into almost any cell in the body—are being widely studied for their role in treating a vast array of human diseases and for generating cells and tissues ...
Cell & Microbiology
Mar 6, 2011
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0
Chemists at The Scripps Research Institute (TSRI) have devised a greatly improved technique for making amino acids not found in nature. These "unnatural" amino acids traditionally have been very difficult to synthesize, but ...
Biochemistry
Mar 13, 2014
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0
Since the ice bucket challenge went viral in 2014, raising awareness and funding for ALS research, scientists have learned much about a disease that disconnects muscles from nerves, leading to muscle atrophy and eventual ...
Biochemistry
Dec 18, 2018
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136
Patients want to see their medical information. Researchers want to share their data.
Analytical Chemistry
Sep 13, 2018
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115
In findings that advance scientists' understanding of a whole class of inherited disorders, a team from The Scripps Research Institute has shed light on a mechanism that enables a potential treatment for Gaucher's disease ...
Biochemistry
May 9, 2010
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0
Bolstering the notion that RNA should be considered an important drug-discovery target, scientists at Scripps Research have found that several existing, FDA-approved anti-cancer drugs may work, in part, by binding tightly ...
Biochemistry
Jun 28, 2018
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115
Picrotoxinin, a plant-derived toxin that Asian fishermen traditionally have used to paralyze and catch fish, has long been seen as a possible starting point for new human therapeutics and other neuroactive products.
Biochemistry
Dec 21, 2023
0
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