The Scripps Research Institute (TSRI) is a biomedical research corporation established in La Jolla, California with another site in Jupiter, Florida. Its origins stem from a large endowment from Ellen Browning Scripps in the 1920s originally targeted for research on immune disorders. In the 1990s the combined Scripps Clinic and Research Institute became separate entitities. Today, TSRI is one of the most prolific and active research institutes in the United States with a wide range of human disorders/conditions in its focus. Namely, cancer biology, cell therapy, genetics, molecular and experimental medicine, neurobiology and more. The newly constructed Scripps Florida focuses on drug discoveries, basic biomedical research and technologies.
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A new "molecular editing" technique from Scripps Research enables chemists to add new elements to organic molecules at locations that were previously out of reach.
Analytical Chemistry
May 31, 2023
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Scripps Research chemists have solved a long-standing problem in the field of pharmaceutical chemistry with a relatively simple and controllable method for making benzocyclobutenes (BCBs)—a class of reactive compounds that ...
Analytical Chemistry
May 11, 2023
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Scripps Research scientists have developed a new strategy for identifying small molecules that can change the function of proteins, offering a promising path for discovering targeted drugs. In collaboration with scientists ...
Biochemistry
Apr 27, 2023
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Two prominent origin-of-life chemists have published a new hypothesis for how the first sugars—which were necessary for life to evolve—arose on the early Earth.
Biochemistry
Apr 13, 2023
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83
An advanced imaging-based method from scientists at Scripps Research offers a new way of studying mitochondria.
Cell & Microbiology
Feb 15, 2023
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88
A new type of polysulfate compound that can form thin, flexible films has properties that could make it a material of choice for many high-performance electrical components, according to a study from chemists and materials ...
Polymers
Jan 18, 2023
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114
To design drugs that stall the growth of aggressive cancers, it helps to know the structures of the proteins that are revving the cancers' engines.
Biochemistry
Dec 9, 2022
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82
Chemists at Scripps Research have devised the first general method for synthesizing a family of compounds called 1,2,3,5-tetrazines, which hold great promise for making pharmaceuticals, biological probes and other chemical ...
Materials Science
Dec 6, 2022
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61
Scientists at Scripps Research have reported success in initial tests of a new, nanotech-based strategy against autoimmune diseases.
Bio & Medicine
Dec 1, 2022
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341
A team led by scientists at Scripps Research and the University of Amsterdam has achieved an important goal in virology: mapping, at high resolution, critical proteins that stud the surface of the hepatitis C virus (HCV) ...
Molecular & Computational biology
Oct 20, 2022
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