St. Jude Children's Research Hospital scientists discovered how the current epizootic H5N1 avian influenza virus (bird flu) gained new genes and greater virulence as it spread west. Researchers showed that the avian virus ...
Evolution
May 30, 2023
0
23
Scientists at St. Jude Children's Research Hospital are studying voltage-gated ion channels (VGICs). Their work revealed a previously unknown mechanism of inactivation for one such channel that plays an important role in ...
Cell & Microbiology
May 20, 2022
0
90
Like a boat helping passengers cross a river, transporters move substances across cell membranes. This process is fundamental to the healthy functioning of cells in life forms from bacteria to humans. The function of these ...
Cell & Microbiology
Nov 13, 2019
0
108
St. Jude Children's Research Hospital scientists have identified a novel structure that helps an enzyme solve a challenging biological problem by bobbing like a ship at the surface of the cell membrane. The finding offers ...
Cell & Microbiology
Jul 24, 2017
0
111
St. Jude Children's Research Hospital molecular biologists have identified an enzyme that activates and "supercharges" cellular machinery that controls how cells become specialized cells in the body.
Cell & Microbiology
Jun 6, 2017
0
110
CTCF is a critical protein known to play various roles in key biological processes such as transcription. Scientists at St. Jude Children's Research Hospital have used a next-generation protein degradation technology to study ...
Biotechnology
Jan 25, 2023
0
22
Like genealogists filling gaps in a family tree, St. Jude Children's Research Hospital scientists have determined that life-long blood production relies on hundreds more "ancestor" cells than previously reported. The study ...
Cell & Microbiology
Sep 18, 2017
0
18
Researchers have determined that the protein nucleophosmin (NPM1) serves as glue that holds proteins and RNA together in the nucleolus and showed how NPM1's structure makes it ideal for the job. St. Jude Children's Research ...
Cell & Microbiology
Mar 1, 2016
0
31
Through an international collaboration, scientists at St. Jude Children's Research Hospital have leveraged data science, pharmacology and structural information to conduct an atomic-level investigation into how each amino ...
Molecular & Computational biology
Dec 21, 2023
0
48
St. Jude Children's Research Hospital investigators are studying the details of how phase separation leads to the formation of RNA granules, assemblies of protein and RNA that are not bound by a membrane. Their findings show ...
Cell & Microbiology
Apr 17, 2020
0
133
