Learning from the bears

Grizzly bears spend many months in hibernation, but their muscles do not suffer from the lack of movement. In the journal Scientific Reports, a team led by Michael Gotthardt reports on how they manage to do this. The grizzly ...

What blocks bird flu in human cells?

Normally, bird flu viruses do not spread easily from person to person. But if this does happen, it could trigger a pandemic. Researchers from the MDC and RKI have now explained in the journal Nature Communications what makes ...

3-D maps of gene activity

A three-dimensional computer model enables scientists to quickly determine which genes are active in which cells, and their precise location within an organ. A team led by Nikolaus Rajewsky, Berlin, and Nir Friedman, Jerusalem, ...

Epigenetic mechanism appears to strongly influence healthy aging

Researchers at the Max Delbrueck Center for Molecular Medicine (MDC) have identified an epigenetic mechanism that appears to strongly influence healthy aging. It's a protein that controls muscle integrity, lifespan and levels ...

Keeping a cell's powerhouse in shape

A German-Swiss team around Professor Oliver Daumke from the MDC has investigated how a protein of the dynamin family deforms the inner mitochondrial membrane. The results, which also shed light on a hereditary disease of ...

Mole rats are pain-free, thanks to evolution

African mole rats are insensitive to many kinds of pain. As an international research team led by the MDC's Gary Lewin reports in Science, this characteristic has allowed mole rats to populate new habitats. Thanks to a genetic ...

On the origin of B1 cells

A new MDC study may resolve a decades-old debate in immunology. A team led by Professor Klaus Rajewsky reports in Science that distinct progenitor cells are not required for the development of B1 cells. Instead, the team's ...

A case of 'kiss and tell': Chromosomal kissing gets less elusive

How are chromosomes arranged in the cell nucleus? Is it possible that they communicate with one another by "touching" each other? To answer this question and to shed more light on the fundamental properties of the communication ...

A complete cell atlas and lineage tree of the immortal flatworm

From one stem cell to many differentiated body cells: Scientists from the MDC in Berlin, along with collaborating researchers in Munich, have published a comprehensive lineage tree of a whole adult animal in the journal Science. ...

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