This article has been reviewed according to Science X's editorial process and policies. Editors have highlighted the following attributes while ensuring the content's credibility:

fact-checked

peer-reviewed publication

trusted source

proofread

3D printed ferroelectric materials proven to eliminate harmful bacteria including E. coli

3D printed ferroelectric materials proven to eliminate harmful bacteria including E. coli
Schematic of the possible selective antimicrobial mechanism of the polarized 3D printed piezo-particulate PCL-BCZT composites. Credit: Advanced Materials Technologies (2023). DOI: 10.1002/admt.202202127

A new way of using 3D printing to create infection-fighting materials for use as medical implants has been revealed in a new research paper, published in Advanced Materials Technologies.

Engineers at the University of Bath, working with colleagues at the University of Ulster, have for the first time successfully created a new kind of ferroelectric composite material with antimicrobial properties using a novel multi-material 3D printing process.

They say the use of electrically responsive ferroelectric materials gives the implants the infection-fighting properties, making them ideal for biomedical applications, such as heart valves, stents and bone implants, reducing the risk of infection for patients.

Reducing risk

While commonplace, all biomedical implants pose some level of risk as materials can carry surface bio-contaminants that can lead to infection. Reducing this risk could be beneficial both to patients in the form of improved outcomes, and to healthcare providers thanks to reduced costs incurred by ongoing treatment.

The team has previously used this 3D printing technique for the fabrication of three-dimensional scaffolds for bone tissue engineering.

Dr. Hamideh Khanbareh, a lecturer in materials and structures in Bath's Department of Mechanical Engineering, is lead author of the research. She says that the development has the scope for wide-ranging applications.

She says, "Biomedical implants that can fight infection or dangerous bacteria such as E. coli could present significant benefits to patients and to health care providers.

"Our research indicates that the ferroelectric composite materials we have created have a great potential as antimicrobial materials and surfaces. This is a potentially game-changing development that we would be keen to develop further through collaboration with medical researchers or health care providers."

Infection-busting properties

The innovation comes thanks to ferroelectricity, a characteristic of certain polar materials that generate electrical surface charge in response to a change in mechanical energy or temperature. In ferroelectric films and implants, this electrical charge leads to the formation of free radicals known as reactive oxygen species (ROS), which selectively eradicate bacteria. This comes about through the micro-electrolysis of water molecules on a surface of polarized ferroelectric composite material.

The used to harness this phenomenon is made by embedding ferroelectric barium calcium zirconate titanate (BCZT) micro-particles in polycaprolactone (PCL) a biodegradable polymer widely used in . The mixture of the ferroelectric particles and polymer is then fed into a 3D bioprinter to create a specific porous "scaffold" shape designed to have a high surface area to promote ROS formation.

Testing showed that even when contaminated with high concentrations of aggressive E. coli bacteria, the composite can completely eradicate the bacteria cells without external intervention, killing 70% within just 15 minutes.

More information: Zois Michail Tsikriteas et al, Additively Manufactured Ferroelectric Particulate Composites for Antimicrobial Applications, Advanced Materials Technologies (2023). DOI: 10.1002/admt.202202127

Journal information: Advanced Materials Technologies

Provided by University of Bath

Citation: 3D printed ferroelectric materials proven to eliminate harmful bacteria including E. coli (2023, April 6) retrieved 25 February 2024 from https://phys.org/news/2023-04-3d-ferroelectric-materials-proven-bacteria.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Explore further

Scientists propose a new filler for bone implants with increased bioactivity

40 shares

Feedback to editors