Despite 132 years of study, no toxin had ever been found for the deadly pathogen Mycobacterium tuberculosis, which infects 9 million people a year and kills more than 1 million.
Cell & Microbiology
Aug 4, 2015
0
77
On the cellular highway, motor proteins called dyneins rule the road. Dyneins "walk" along structures called microtubules to deliver cellular cargo, such as signaling molecules and organelles, to different parts of a cell. ...
Biochemistry
Feb 9, 2018
0
498
Researchers at the Francis Crick Institute have characterised the structure of the SARS-CoV-2 spike protein as well as its most similar relative in a bat coronavirus. The structures provide clues about how the spike evolved ...
Evolution
Jul 9, 2020
0
46
An antimicrobial compound made by honeybees could become the basis for new antibiotics, according to new research at the University of Illinois at Chicago.
Cell & Microbiology
Sep 7, 2017
0
392
Powerful opiate drugs are a mainstay in modern medicine, alleviating pain in both acute and chronic forms. These charms however, bear a curse. Users quickly develop tolerance to their effects, requiring ever-increasing doses ...
Biochemistry
Mar 2, 2015
0
612
A protein complex prevents the repair of genome damage in human cells, in mice and in the nematode Caenorhabditis elegans, a team of researchers at the University of Cologne has discovered. They also successfully inhibited ...
Cell & Microbiology
Mar 23, 2023
0
196
Environmental conditions, lifestyle choices, chemical exposure, and foodborne and airborne pathogens are among the external factors that can cause disease. In contrast, internal genetic factors can be responsible for the ...
Molecular & Computational biology
May 21, 2019
0
171
Serotonin, known as the "happiness" neurotransmitter, is a chemical found in the body responsible for feelings of well-being. But serotonin isn't the only chemical that binds to the 13 serotonin receptors found on the surface ...
Biochemistry
Aug 20, 2018
0
333
The human glutamine transporter ASCT2 is upregulated in several forms of cancer. It is also the docking platform for a wide range of pathogenic retroviruses. A team of University of Groningen scientists have used cryo-electron ...
Biochemistry
Jun 6, 2018
0
767
In a complex called chromatin, long strands of DNA in cells' nuclei are tightly wrapped around a scaffolding of proteins, like a rolled-up ball of yarn. A new study by Weill Cornell Medicine investigators reveals that beyond ...
Cell & Microbiology
Jan 2, 2024
0
70
