Using highly sensitive fluorescent probes, a team of scientists from the University of Connecticut has captured the never-before-seen structural dynamics of an important protein channel inside the cell's primary power plant ...
Cell & Microbiology
Jul 7, 2013
0
0
In a new study, researchers from the Case Western Reserve University School of Medicine have identified the structure of protein fibrils linked to a hereditary form of human prion disease. This insight, they say, reveals ...
Cell & Microbiology
Sep 12, 2022
0
142
Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form a node known as the transcription ...
Biotechnology
Jul 3, 2024
0
49
Researchers at The Wistar Institute have uncovered new aspects of the three-dimensional organization of the genome, specifically how the genetic material is compacted and de-compacted in a timely fashion during the different ...
Cell & Microbiology
Oct 9, 2017
0
499
As the world scrambles to control the growing COVID-19 coronavirus pandemic, new research in Nature Structural & Molecular Biology shows viruses also play a key evolutionary role in mammals' ability to reproduce and survive.
Molecular & Computational biology
Sep 7, 2020
1
281
During early encounters between a pathogen and a cell, receptors located on the cell surface, in the cytosol or within endosomal (storage) compartments engage with the pathogen's nucleic acid (DNA/RNA) or pathogen-associated ...
A team led by scientists at The Scripps Research Institute (TSRI) has determined the basic structural organization of a molecular motor that hauls cargoes and performs other critical functions within cells.
Cell & Microbiology
Mar 9, 2015
0
2425
Scientists from The Scripps Research Institute and the US Army's Medical Research Institute of Infectious Diseases have isolated and analyzed an antibody that neutralizes Sudan virus, a major species of ebolavirus and one ...
Cell & Microbiology
Nov 21, 2011
0
0
Building on earlier work exploring the complex choreography by which intricate cellular proteins interact with and copy DNA prior to cell division, scientists at the U.S. Department of Energy's Brookhaven National Laboratory ...
Cell & Microbiology
Jul 14, 2013
0
0
The discovery of long non-coding RNA (lncRNA) has dramatically changed the understanding of the biology of diseases such as cancer. The human genome contains about 20,000 protein-coding genes - less than 2 percent of the ...
Cell & Microbiology
Apr 28, 2016
0
647
