Prime editing enables precise gene editing without collateral damage
The latest gene editing technology, prime editing, expands the 'genetic toolbox' for more precisely creating disease models and correcting genetic problems, scientists say.
The latest gene editing technology, prime editing, expands the 'genetic toolbox' for more precisely creating disease models and correcting genetic problems, scientists say.
Biotechnology
Mar 30, 2021
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32
Instruments, even expensive, high-tech ones like DNA sequencing machines, aren't perfect. Researchers use sequencers to decode the chemical bases that make up DNA, the blueprint of life. The devices play a key role in cancer ...
Biotechnology
Mar 18, 2021
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0
RNA is the central tenet of molecular biology, the stepping-stone between DNA and proteins.
Biotechnology
Feb 4, 2021
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572
The idea struck Robert Ietswaart, a research fellow in genetics at Harvard Medical School, while he was trying to determine how an experimental drug slowed the growth of lung cancer cells.
Biotechnology
Feb 2, 2021
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82
Genetic rewiring could have driven an evolutionary explosion in the shapes, sizes and adaptations of cichlid fish, in East Africa's answer to Darwin's Galapagos finches.
Evolution
Jan 19, 2021
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14
Researchers from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences developed a method termed SCRaMbLE-based genome compaction (SGC) to revamp and minimize the yeast genome.
Biotechnology
Jan 8, 2021
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6
Bacteria often show very strong biogeography—some bacteria are abundant in specific locations while absent from others—leading to major questions when applying microbiology to therapeutics or probiotics: how did the bacteria ...
Cell & Microbiology
Dec 19, 2020
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141
From the perspective of A. Murat Eren, Ph.D., the mouth is the perfect place to study microbial communities. "Not only is it the beginning of the GI tract, but it's also a very special and small environment that's microbially ...
Cell & Microbiology
Dec 16, 2020
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220
Similar to genetic mutations, epigenetic changes, i.e. gene modifications that do not occur on the primary DNA sequence, sometimes arise accidentally in plants and can be transmitted across generations. Using trees as a model, ...
Plants & Animals
Nov 18, 2020
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68
The lack of certain genes in the BEC/TCEAL cluster could be related to alterations associated with autism spectrum disorder, according to a preclinical study published in the journal Genome Biology and led by Professor Jordi ...
Cell & Microbiology
Oct 26, 2020
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73