Genomics is a discipline in genetics concerned with the study of the genomes of organisms. The field includes efforts to determine the entire DNA sequence of organisms and fine-scale genetic mapping. The field also includes studies of intragenomic phenomena such as heterosis, epistasis, pleiotropy and other interactions between loci and alleles within the genome. In contrast, the investigation of the roles and functions of single genes is a primary focus of molecular biology or genetics and is a common topic of modern medical and biological research. Research of single genes does not fall into the definition of genomics unless the aim of this genetic, pathway, and functional information analysis is to elucidate its effect on, place in, and response to the entire genome s networks. For the United States Environmental Protection Agency, "the term "genomics" encompasses a broader scope of scientific inquiry associated technologies than when genomics was initially considered. A genome is the sum total of all an individual organism s genes. Thus, genomics is the study of all the genes of a cell, or tissue, at the DNA (genotype), mRNA (transcriptome), or protein (proteome) levels." The

Publisher
BioMed Central
Country
United Kingdom
History
2000–present
Website
http://genomebiology.com
Impact factor
6.89 (2011)

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Cross species transfer of genes has driven evolution

Far from just being the product of our parents, University of Adelaide scientists have shown that widespread transfer of genes between species has radically changed the genomes of today's mammals, and been an important driver ...

African populations crossbred with other extinct humans

A new international study led by David Comas, principal investigator at UPFand at the Institute of Evolutionary Biology (IBE: CSIC-UPF), demonstrates for the first time using artificial intelligence that African populations ...

Kiwi bird genome sequenced

Its unusual biological characteristics make the flightless kiwi a unique kind of bird. Researchers of the University of Leipzig and the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, have now sequenced ...

Ancient wild ox genome reveals complex cow ancestry

The ancestry of domesticated cattle proves more complex than previously thought, reports a paper published today in the open access journal Genome Biology. The first nuclear genome sequence from an ancient wild ox reveals ...

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