Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, Scripps Research chemists have demonstrated new custom-designed ...
Biochemistry
Mar 13, 2024
0
11
A new solvatochromic probe could help shed light on the relationship between lipid membrane fluidity and various cellular functions, report scientists at Tokyo Institute of Technology and Kyushu University. Thanks to an innovative ...
Biochemistry
Mar 12, 2024
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46
Semaglutide is part of the glucagon-like peptide-1 (GLP-1) receptor targeting family of peptide drugs which are mainly used to treat diabetes but are difficult and expensive to make.
Biochemistry
Mar 12, 2024
0
68
Natural products have unique chemical structures and biological activities and can play a pivotal role in advancing pharmaceutical science. In a study published in Heliyon, researchers from Shinshu University have discovered ...
Biochemistry
Mar 11, 2024
0
73
Peptides are short strands of amino acids that are increasingly used therapeutically, as biomaterials and as chemical and biological probes. The capacity to isolate, manipulate and label peptides and larger proteins is limited, ...
Biochemistry
Mar 11, 2024
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148
Water determines life: humans are three-quarters water. An international research team led by the University of Amsterdam (UvA) has now discovered how water also determines the structure of the material that holds us together: ...
Biochemistry
Mar 8, 2024
1
71
Helicases are enzymes that unwind DNA and RNA. They're central to cellular life, implicated in a number of cancers and infections—and, alas, extraordinarily difficult to target with drugs.
Biochemistry
Mar 7, 2024
0
31
A pair of chemists at the University of Groningen in the Netherlands, has observed communication between rotors in a molecular motor. In their study, reported in the Journal of the American Chemical Society, Carlijn van Beek ...
Boston College researchers used a mild charge of electricity to precisely modify proteins, a new tool that can be used to develop novel biotherapeutics and protein-based research tools, the team reported recently in the journal ...
Biochemistry
Mar 5, 2024
0
99
Millions of people around the world drink coffee every day. The beverage contains a large number of bioactive substances, and its health effects on the human metabolism are therefore frequently subjects of scientific studies. ...
Biochemistry
Mar 4, 2024
0
45
