How boron helps to produce key proteins for new cancer therapies

Chemists from ETH Zurich have found a way to produce poorly soluble proteins by caging a uniquely reactive boron compound. This method opens up new possibilities for the synthesis of tailored protein therapeutics, including ...

Unlocking the hidden pocket on a billion‑dollar drug target

For years, a protein inside our cells has quietly powered billions of dollars' worth of cancer drugs. Now a team of researchers have discovered that this workhorse protein, called cereblon, in addition to its known functions, ...

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