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Biochemistry news
Scientists create vast library of compounds to target disease proteins
Over the past two decades, large genetic studies have linked tens of thousands of DNA variants to thousands of human traits and diseases. Yet, correcting the effects of those variants to treat disease has been hampered in ...
Biochemistry
15 hours ago
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40
Scientists identify 11 genes affected by PFAS, shedding light on neurotoxicity
Per- and polyfluorinated alkyl substances (PFAS) earn their "forever chemical" moniker by persisting in water, soil and even the human brain. This unique ability to cross the blood-brain barrier and accumulate in brain tissue ...
Biochemistry
16 hours ago
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104
Freely accessible database maps protein-lipid interactions for research and education
From combating cancer and infections to storing energy, lipid-protein interactions are critical to biological processes in cells. But the mechanisms that drive these interactions have historically been difficult to map and ...
Biochemistry
16 hours ago
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25
How a single nitrogen atom could transform the future of drug discovery
Researchers at the University of Oklahoma have developed a breakthrough method of adding a single nitrogen atom to molecules, unlocking new possibilities in drug research and development. Now published in the journal Science, ...
Biochemistry
16 hours ago
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85
Electron microscopy captures enzyme step in antibiotic production
Nonribosomal peptide synthetase (NRPS) enzymes are essential in creating important medications, such as penicillin and cyclosporine. This is done through a multi-step process where the enzymes activate amino acid building ...
Biochemistry
18 hours ago
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35
Virtual chemistry synthesizes 25 variations of a plant compound that could treat brain diseases
Among the hundreds of thousands of chemical compounds produced by plants, some may hold the key to treating human ailments and diseases. But recreating these complex, naturally occurring molecules in the lab often requires ...
Biochemistry
20 hours ago
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46
How do mosquito repellents work? A chemistry expert explains
It's summertime, and for many of us that means plenty of time outside—and, unfortunately, mosquitoes.
Biochemistry
20 hours ago
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1
Small milk fat globules promote growth of good bacteria, study reveals
A new study has unveiled fascinating insights into the complex relationship between milk fat globules and bacteria. The research, published in Food Chemistry, explores how the structural properties of these microscopic fat ...
Biochemistry
Jan 2, 2025
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32
Deep neural networks enhance fragrance design with scent predictions
Researchers have explored the potential of deep neural networks (DNNs) in transforming fragrance design. By analyzing the sensing data of 180 essential oils, the DNN was trained using the odor descriptor data from 94 essential ...
Biochemistry
Jan 2, 2025
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50
Microplastics found in multiple human organ tissues correlated with lesions
Research led by Zhejiang Agriculture and Forestry University in China has performed a metadata investigation into the presence of microplastics in humans. They report a concerning relationship between micro and nanoplastic ...
Enhanced Raman microscopy offers clearer chemical imaging of cryofixed samples
Understanding the behavior of the molecules and cells that make up our bodies is critical for the advancement of medicine. This has led to a continual push for clear images of what is happening beyond what the eye can see. ...
Biochemistry
Dec 24, 2024
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77
Biosensors mimic human olfactory system to discriminate between very similar odors
The human olfactory system discriminates between thousands of odors by interacting specifically with olfactory receptors on sensory neurons. Each receptor can detect several odorants at different intensities, and the same ...
Biochemistry
Dec 20, 2024
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3
Researchers highlight role 'workhorse protein' plays in keeping nervous system running smoothly
A team of researchers from the University of Massachusetts Amherst is the first to show how proteins called "chaperones" are vital in ensuring that neurons can transmit signals to one another. When this neurotransmission ...
Biochemistry
Dec 19, 2024
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Researchers develop edible biofilm for extending fruit shelf life
With significant improvements in transportation technology, the accessibility of fresh food has considerably increased. However, this progress has been accompanied by escalating concerns about food waste during transportation ...
Biochemistry
Dec 18, 2024
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Nature's instructions: How fungi make a key medicinal molecule
For roughly a century, ever since Alexander Fleming's accidental discovery of penicillin in 1928, fungi have proven to be a goldmine for medicines. They've provided treatments for a wide range of diseases, from infections ...
Biochemistry
Dec 18, 2024
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22
Potentially harmful bacteria can slip through antimicrobial showerheads, study finds
To guard against harmful waterborne pathogens, many consumers, including managers of health-care facilities, install antimicrobial silver-containing showerheads. But in ACS ES&T Water, researchers now report that these fixtures ...
Biochemistry
Dec 18, 2024
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1
Azo-menthol: New molecule can regulate ion channels using light
Located in the cell membrane, TRPM8 ion channels are known as receptors that recognize cold and respond to menthol, the cooling agent in peppermint. In addition, these channels influence pain perception and play a key role ...
Biochemistry
Dec 18, 2024
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71
Novel platinum complex shows strong antiproliferative effects with low toxicity in preclinical prostrate cancer models
Prostate cancer remains a global health challenge, ranking as the second most commonly diagnosed cancer among men. Although treatments like androgen deprivation therapy have been effective for early-stage prostate cancer, ...
Biochemistry
Dec 16, 2024
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1
Why does red wine cause headaches? Research points to a compound found in the grapes' skin
Medical accounts of red wine headaches go back to Roman times, but the experience is likely as old as winemaking—something like 10,000 years. As chemists specializing in winemaking, we wanted to try to figure out the source ...
Biochemistry
Dec 16, 2024
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Hydrogen's dual nature helps reveal hidden catalytic processes
Microorganisms have long used hydrogen as an energy source. To do this, they rely on hydrogenases that contain metals in their catalytic center. In order to use these biocatalysts for hydrogen conversion, researchers are ...
Biochemistry
Dec 13, 2024
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