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Nature's instructions: How fungi make a key medicinal molecule

For roughly a century, ever since Alexander Fleming's accidental discovery of penicillin in 1928, fungi have proven to be a goldmine for medicines. They've provided treatments for a wide range of diseases, from infections ...

Azo-menthol: New molecule can regulate ion channels using light

Located in the cell membrane, TRPM8 ion channels are known as receptors that recognize cold and respond to menthol, the cooling agent in peppermint. In addition, these channels influence pain perception and play a key role ...

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Biochemistry
Why does red wine cause headaches? Research points to a compound found in the grapes' skin
Biochemistry
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Hydrogen's dual nature helps reveal hidden catalytic processes
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Biochemistry
Fast, rewritable computing with DNA origami registers
Biochemistry
Super-enzyme can enhance CO₂ capture in extreme conditions
Biochemistry
Simple, eco-friendly technique uses bacteria to produce vitamin B2 naturally
Biochemistry
E. coli dons polymer 'Superman cape' for sustainable chemical production
Biochemistry
New antidote could save lives from deadly hydrogen sulfide gas
Biochemistry
Researchers uncover the physical chemistry behind tick adhesion to skin
Biochemistry
Pain relief research: Naturally occurring hederagenin found to bind to the pain regulation receptor
Biochemistry
In vivo electrochemistry could provide early detection of high-altitude hypoxic brain injury
Biochemistry
Advances in carotenoid analysis: Speed and precision unlocked
Biochemistry
Discovery of diverse daphnane diterpenoids in Daphne pontica
Biochemistry
A new method for efficient synthesis of anti-cancer drugs
Biochemistry
Analysis method reveals unknown chemicals in human serum samples
Biochemistry
Chemists develop color-changing test for rapid salmonella detection
Biochemistry
Scientists streamline creation of nucleoside analogs, a group of life-saving molecules
Biochemistry
Study discovers a nano-switch mechanism controlled by a single hydrogen atom in all living organisms
Biochemistry
How a middle schooler found a new compound in a piece of goose poop

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Astronomy
The LZ experiment's first science run sets new constraints on dark matter interactions
Soft Matter
Simulations of supercooled liquid molecular dynamics may lead to higher-quality glass production at lower cost
Space Exploration
NASA eyes SpaceX, Blue Origin to cut Mars rock retrieval costs
Space Exploration
US company Firefly Aerospace to launch for moon next week
Astronomy
Origins of black holes are revealed in their spin, gravitational wave data analysis finds
Earth Sciences
Sunken worlds under the Pacific? High-res models reveal workings of Earth's mantle
Earth Sciences
Earth's air war: Explaining the delayed rise of plants and animals on land
Astronomy
Astronomers find massive supernova remnant closer than previously thought
Plants & Animals
19 times a day: Male medaka mating limits revealed
Quantum Physics
The first observation of time-domain oscillations between two distant semiconductor spin qubits
Ecology
Snail darter revisited: Famous fish that halted a dam's construction is not endangered after all
General Physics
Nickel-58 nucleus may host elusive toroidal dipole excitations
Plants & Animals
Rare video captures following and biting courtship behavior in elusive whale sharks
Space Exploration
NASA proposes cheaper, quicker way to get Mars rocks and soil to Earth
Polymers
Ring-shaped polymers solidify into glass, offering sustainable material potential
Earth Sciences
Groundwater simulation uncovers hidden paths and long-distance flows on a continental scale
Other
Reexamining the Prisoner's Dilemma: Study finds diversity and context play a larger role than thought
Optics & Photonics
AI technique generates clear images of thick biological samples without additional hardware
Plants & Animals
Your stress levels also affect your dog, heart rate study shows
Bio & Medicine
Scientists develop nanobody inhibitors to target deadly Ebola virus

Chemical trick activates antibiotic directly at the pathogen

Colistin is a last-resort antibiotic that is usually only used for severe infections with resistant bacteria. This is due to its severe kidney-damaging side effects, which occur in about 30% of treated patients. A research ...