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Drug building blocks pave path to new sepsis treatments

The immune system can typically ramp up the body's defenses to clear out an invading threat without issue. Glitches can happen, however, with sepsis occurring when the mustered army of cells also attacks the body's own tissues ...

First images capture cholesterol crystal formation in the body

A pair of University of Houston professors, known for their contributions to crystal engineering with specific breakthroughs in the design of therapeutics to prevent crystallization in human diseases, are discovering how ...

Packets of freeze-dried bacteria can grow biocement on demand

Cement manufacturing and repair could be significantly improved by using biocement-producing bacteria, but growing the microbes at construction sites remains a challenge. Now, researchers report a freeze-drying approach in ...

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Biochemistry
From coral to lab: Understanding biflorane synthase for bioactive compound production
Biochemistry
Artificial photosynthesis converts organic waste into useful pharmaceuticals and energy
Biochemistry
Quantum mechanics and molecular dynamics reveal opioid binding complexities
Biochemistry
Protein cage system can control conformational changes in aromatic side chains
Biochemistry
Fragment-based drug design: New method searches through 10 sextillion molecules
Biochemistry
A contradictory protein readily accepts electrons despite having a strongly negative charge
Biochemistry
Scientists invent new drug candidates to treat antibiotic-resistant bacteria
Biochemistry
Biobased lignin gels offer sustainable alternative for hair conditioning
Biochemistry
New carbon–phosphorus stapled Au compound with cancer-fighting properties
Biochemistry
Synthesis method unlocks a pathway to valuable fluorinated drug compounds for new medicines
Biochemistry
Surprise discovery shows zinc-carrying proteins can activate acid reducing drugs without the presence of gastric acid
Biochemistry
Discovery of high-spin manganese centers sheds light on photosynthesis
Biochemistry
Machine learning powers detection of contamination, spoilage in dairy, meat
Biochemistry
Thermophilic bacterium achieves high conversion rate for plastic recycling
Biochemistry
Engineers create new glue that mimics mussels and mucus to prevent bacterial buildup
Biochemistry
Researchers create a new material from tree nuts with broad medical applications
Biochemistry
Scaling sustainable carbon fiber production: A breakthrough in lignin-based technology
Biochemistry
New findings on the power of enzymes could reshape biochemistry
Biochemistry
New approach identifies reproducible volatile organic compounds for lung cancer diagnosis
Biochemistry
Leveraging a novel protein tagging strategy offers new route to cancer treatment

Other news

General Physics
Why does nature love spirals? The link to entropy
Optics & Photonics
Boosting the response speed of quantum LEDs via an excitation memory effect
Quantum Physics
D-Wave claims its quantum computers can solve a problem of scientific relevance much faster than classical methods
Other
Saturday Citations: A baffling discovery from Webb; the face of an early human; humans and dogs like to chill together
Ecology
Study finds chain-link fences reduce predator attacks on livestock
Space Exploration
Crew launch to ISS paves way for 'stranded' astronauts' return
Evolution
Genomic study indicates our capacity for language emerged 135,000 years ago
Astrobiology
'Microlightning' in water droplets may have sparked life on Earth
Quantum Physics
Quantum entanglement wins: Researchers report quantum advantage in a simple cooperation game
Plants & Animals
How a rapidly growing population of crocs has been impacting Australia's Northern Territories ecosystem
Paleontology & Fossils
Melanosome patterns in Mesozoic mammals suggest they had dark, uniformly dull fur coloring
Archaeology
Smell like a god: Ancient sculptures were scented, Danish study shows
Earth Sciences
Earthquake rupture patterns reveal Mamara fault directs considerable seismic energy towards Istanbul
Bio & Medicine
Unveiling cancer's hidden messengers: How extracellular vesicles aid tumor spread
Optics & Photonics
Physicists use optical vortex beams to control atom ionization
Astronomy
TOI-1453 c: A key sub-Neptune discovered in a system of two exoplanets
Environment
Smoke from wildland-urban interface fires deadlier than remote wildfires, study finds
Condensed Matter
Understanding the origin of magnetic moment enhancement in novel alloys
Cell & Microbiology
Tapuy rice wine fermentation yields possible anti-aging superfood
Bio & Medicine
Biomolecular 'silly putty': High-res imaging of cellular condensates achieved using fluorogen technology

A new approach to building 3D molecules for better drugs

A report in the journal Science from researchers in the UW–Madison Department of Chemistry represents a significant advance in making the types of molecules needed in drug development. Molecules with three-dimensional complexity ...

Copper radical mimics enzyme for highly efficient C-H oxidation

Optically pure alcohols are prevalent motifs in natural products and pharmaceuticals, driving the development of effective methods for their synthesis. Since the first reports of the Kharasch-Sosnovsky reaction in 1958, the ...

Scientists uncover key step in how diazotrophs 'fix' nitrogen

Nitrogen is an essential component in the production of amino acids and nucleic acids—both necessary for cell growth and function. Although the atmosphere is composed of nearly 80% nitrogen, this nitrogen is in the form ...