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Biochemistry news
Jamming bacterial communications, instead of killing the microbes, might provide long-lasting treatment
Every minute, nearly 500 antibiotic prescriptions are written in the U.S. Many of these drugs succeed, but more are being outmaneuvered by resistant bacteria. This can lead to tragic results, like the death of one Nevada ...
Biochemistry
15 hours ago
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Frustrated Lewis pair chemistry enables dual atom insertion to build bioactive molecules
Researchers from the National University of Singapore (NUS) have developed a boron-catalyzed method to transform oxetanes, which are small four-membered ring molecules, into larger, medicinally relevant 1,3-oxazinanes by ...
Biochemistry
16 hours ago
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Decoding sugars one bond at a time—without labels
Researchers at National Taiwan University have developed a tip-enhanced Raman spectroscopy platform that can identify tiny structural differences in oligosaccharides without fluorescent labels. The method can distinguish ...
Biochemistry
19 hours ago
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Synthesis of amino acids from carbon reaches 97% efficiency with cell-free system
The building blocks of proteins, amino acids, are essential for all living things. Twenty different amino acids build the thousands of proteins that carry out biological tasks. While some are made naturally in our bodies, ...
Biochemistry
Mar 20, 2026
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'Plastic-eating' fusion enzyme improves polyester textile recycling
In a new study, scientists from the universities of Portsmouth and Manchester report that a specially engineered enzyme can significantly speed up the breakdown of PET—the plastic used in water bottles, food packaging and ...
Biochemistry
Mar 20, 2026
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Light-activated medicines may cut side effects: How a switchable beta blocker works
Rendering a drug effective or ineffective in a flash at the appropriate location—this is the focus of research in photopharmacology. The goal is to develop drugs that can be switched on and off with light of a specific ...
Biochemistry
Mar 19, 2026
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Fluorescent dye that works in superacidic conditions expands possibilities for imaging in extreme environments
Since the 1960s, boron–dipyrromethene dyes, commonly called BODIPY dyes, have been widely used for their strong fluorescence, especially in bioimaging, molecular and ion sensing, and as photosensitizers. Researchers especially ...
Biochemistry
Mar 19, 2026
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White-rot fungi show promise for reducing pharmaceutical residues in biosolids
Antidepressants and other psychoactive drugs are designed to affect the human brain. But after they enter the water system in excrement or unused drugs flushed down the drain, traces of these compounds can enter the environment ...
Biochemistry
Mar 18, 2026
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Cell-inspired sensor can monitor blood for 10 hours without sensitivity loss
A team led by La Trobe University has drawn inspiration from nature to develop a breakthrough sensor that can rapidly track tiny molecular changes in blood, paving the way to real-time, personalized medicine. The discovery ...
Biochemistry
Mar 18, 2026
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Most mass spectrometers can process just a few molecules at once: Reengineered prototype does a billion simultaneously
Mass spectrometry is already a powerful tool for determining what kind and how many molecules are present in a given sample. But most instruments still analyze their molecules one or just a few at a time, an approach that ...
Biochemistry
Mar 18, 2026
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308
A 'two-factor authentication' system that controls microRNA destruction
Cells rely on tiny molecules called microRNAs to tune which genes are active and when. Cells must carefully control the lifespan of microRNAs to prevent widespread disruption to gene regulation. A new study led by researchers ...
Biochemistry
Mar 18, 2026
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Mystery of quinine biosynthesis solved with newly discovered enzymes
For over 350 years, quinine and other extracts from the cinchona tree (Cinchona spp.) were the only effective medicines against malaria, a tropical fever caused by single-celled parasites of the genus Plasmodium and transmitted ...
Biochemistry
Mar 18, 2026
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Snail-derived compound could be a safer anticoagulant compared to heparin
For more than a century, heparin has been the go-to anticoagulant to prevent harmful blood clots in blood vessels or the heart from forming or getting larger. However, a major side effect is an increased risk of excessive ...
Biochemistry
Mar 18, 2026
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AI model predicts chemical effects on gene expression, speeding drug discovery
Inside a diseased cell, the genes are in chaos. Some are receiving signals to overproduce a protein. Others are reducing activity to abnormal levels. Up is down and down is up. The right molecule could restore order, reversing ...
Biochemistry
Mar 17, 2026
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Not one ring but many: Antioxidant enzyme family can assemble in far more diverse ways than previously thought
Peroxiredoxins are among the most abundant enzymes involved in managing oxidative stress. They control the levels of peroxides such as hydrogen peroxide, relay redox signals, and help protect other proteins during stress. ...
Biochemistry
Mar 14, 2026
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69
Deep-sea natural compound targets cancer cells through a dual mechanism
A collaborative research team has uncovered a previously unknown mechanism of action of yaku'amide B, a structurally complex peptidic natural product derived from deep-sea sponge found in the waters near Yakushima Island, ...
Biochemistry
Mar 14, 2026
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288
NMR reveals site-specific structural signatures of therapeutic antibodies without isotope labeling
Monoclonal antibodies are widely used to treat diseases ranging from cancer to autoimmune disorders. The safety and efficacy of these biologic drugs depend on maintaining their correct three-dimensional organization, known ...
Biochemistry
Mar 14, 2026
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How an alga makes the most of dim light by rearranging ordinary chlorophyll
To survive in areas where it is difficult to photosynthesize, some organisms adopt unique strategies. Osaka Metropolitan University researchers have found that a freshwater alga captures far-red light as an additional energy ...
Biochemistry
Mar 13, 2026
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Cloud-ready simulation framework enables capture of molecular binding pathways
Researchers at the Center for Computational Sciences, University of Tsukuba, have developed an accessible platform to overcome the limitations of conventional static docking simulations, offering new avenues for education, ...
Biochemistry
Mar 13, 2026
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Failed experiment leads to surprise drug development breakthrough
Scientists at the University of Cambridge have developed a new way to alter complex drug molecules using light rather than toxic chemicals—a discovery that could accelerate and improve how medicines are designed and made. ...
Biochemistry
Mar 12, 2026
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Study reshapes understanding of interaction between organelles in animal cells
