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This giant virus just gave up its atomic blueprint

A research group has successfully determined, for the first time in the world, the capsid (outer shell) structure of Melbournevirus—a member of the giant virus family—at a resolution of 4.4 Å using cryo-electron microscopy ...

Examining embryo model ethics beyond box-checking

In science, ethical guidelines ensure that research takes place in a way that respects public trust and is conducted responsibly. Traditional ethics approval procedures work well for projects following established practices, ...

A 'stemness checkpoint' helps control stem cell identity

A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental stages. For nearly two decades, ...

Glucose transport may hinge on a fleeting transition-like state

Stockholm University and SciLifeLab researchers have uncovered how glucose transporters move nutrients into cells, bridging a long-standing gap between structure and function in membrane biology. "Our study shows that these ...

AI uncovers hidden immune defenses inside bacteria

Researchers at the Massachusetts Institute of Technology (MIT) have discovered thousands of new proteins that protect bacteria from virus attacks using an AI system called DefensePredictor. What would usually take months ...

Split shift: A surprising twist in the biology of aging

A new Yale study of flatworms, a species with the unique ability to regenerate, reveals that disruptions in the body's internal map of cellular organization may play a part in age-related decline.

Researchers clarify how cells remove damaged endoplasmic reticulum

The cell's endoplasmic reticulum (ER) plays a central role in protein synthesis, folding, and calcium (Ca²⁺) storage. When damaged, ER-phagy (self-eating) removes affected ER regions via double-membrane vesicles called autophagosomes. ...

Cell 'snowball' may be answer to large-scale tissue engineering

Cell cultures—single layers of cells grown in a small dish—have enabled researchers to study biological growth, develop or test drugs and even discover what causes some diseases. Cell spheroids, 3D versions of cell cultures ...

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Cell & Microbiology
Scientists identify potential new target for disrupting mosquito reproduction
Cell & Microbiology
Stopping algae blooms with bacteria-busting buoys
Cell & Microbiology
Bacterial enzyme uses a donut-shaped ring to shred tough collagen, study reveals
Cell & Microbiology
How mitochondria organize our 'second genome'
Plants & Animals
Cell lineage tracing reveals early‑segregated germline in plants
Cell & Microbiology
This tiny organism simply loves corners, using geometry to sense its world
Cell & Microbiology
Engineered E. coli dependency may help contain microbes to defined areas
Cell & Microbiology
DNA-binding protein blocks virulence cascade in a diarrhea pathogen outside hosts, study finds
Cell & Microbiology
Precision work prior to cell division: How enzymes optimize DNA structure
Cell & Microbiology
Atomic-level simulations reveal rotational mechanism behind a critical biomolecular motor
Cell & Microbiology
One of cholera's great enemies is found in the human gut
Cell & Microbiology
Soil biodiversity linked to lower human infectious disease risk
Cell & Microbiology
How plants fight back against bacteria that promote waterlogging in leaves
Ecology
Air surveillance reveals hidden reservoirs of antibiotic resistance genes
Cell & Microbiology
SimCells successfully target and kill drug-resistant bacteria
Cell & Microbiology
Forest soil on doormats rebalances urban homes' indoor microbiome, study suggests
Ecology
Getting a glimpse of viral dances in the dark in the Sargasso Sea
Cell & Microbiology
Targeting the tiniest divide: Research reveals potential vulnerability in bacterial reproduction
Cell & Microbiology
Viruses 'eavesdrop' on each other—but it can backfire
Cell & Microbiology
Study reveals mechanisms underlying oxygen-tolerant energy conversion in a marine photosynthetic bacterium

Other news

Plants & Animals
Chimpanzee empire falls apart in rare instance of division and deadly violence
Biotechnology
AI-designed proteins built from scratch can recognize specific compounds
Evolution
Mammal ancestors laid eggs—and this 250-million-year-old fossil proves it
Archaeology
No more giants, no more heavy handaxes: Why early humans downsized their stone tools
Analytical Chemistry
Plant-inspired water membrane filters CO₂ with constant selectivity and adjustable permeance
Environment
Street green space can help cool cities, but it will not be enough on its own
Social Sciences
Hat wars of early modern England reveal how manners make the rebel
Biotechnology
AI diffusion models tailor drug molecules to custom-fit protein targets, speeding drug development and evaluation
Nanomaterials
Carbon nanotube fiber sensors achieve record measurement error below 0.1%
Environment
Non-producing oil and gas wells may emit microbial methane at rates 1,000 times higher than previously estimated
Analytical Chemistry
Hydroxyl radicals in UV-exposed water reveal surprising reaction pathway
Optics & Photonics
Megawatt structured light arrives with 3,070 optical vortices in one array
Astronomy
What if dark matter came in two states?
Molecular & Computational biology
A smarter way to build vaccines: Scientists harness AI to target emerging alphaviruses
Plants & Animals
Oxygen sensing helps explain why amphibians regenerate limbs but mammals cannot
Earth Sciences
Deadly heat thresholds have already being crossed in six recent heat waves, study shows
Social Sciences
Integrative experiment design reveals hidden patterns in decades-old social science research
Biochemistry
Nickel catalyst enables precision mirror-image assembly for key drug scaffolds
Biochemistry
How surface chemistry impacts the performance of malaria nets
Mathematics
Mathematical signature spots when competition is fair, winner-take-all, or too soft

Revealing the cell's nanocourier at work

An international group of researchers led by Pompeu Fabra University has discovered the nanomachine that controls constitutive exocytosis: the uninterrupted delivery of spherical molecular packages to the cell surface. This ...

How actin wavefronts rescue T cell receptors from endocytosis

Every time our body encounters a new disease-causing agent, a crucial defense system called adaptive immunity comes into play. T cells, the top agents in this system, survey the internal environment of infected cells and ...

Insights into the logistics of cellular waste disposal

Protein aggregates, damaged organelles, and invading bacteria are identified and removed in healthy cells. An international research team led by Professor Konstanze F. Winklhofer from the Institute of Biochemistry and Pathobiochemistry ...